Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer

Yttrium-90 microsphere selective internal radiation therapy (90Y-SIRT) has been widely used in the treatment of malignant liver cancers, and its safety and efficacy have been fully validated. As an important local therapeutic method, 90Y-SIRT has been utilized for the treatment of multiple metastati...

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Main Authors: Guanxiang ZHUO, Linhe GAN, Jinfeng LIAN, Yilin WANG
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2025-02-01
Series:Zhongguo Linchuang Yixue
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Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20241533
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author Guanxiang ZHUO
Linhe GAN
Jinfeng LIAN
Yilin WANG
author_facet Guanxiang ZHUO
Linhe GAN
Jinfeng LIAN
Yilin WANG
author_sort Guanxiang ZHUO
collection DOAJ
description Yttrium-90 microsphere selective internal radiation therapy (90Y-SIRT) has been widely used in the treatment of malignant liver cancers, and its safety and efficacy have been fully validated. As an important local therapeutic method, 90Y-SIRT has been utilized for the treatment of multiple metastatic liver cancers in many cancer diagnosis and treatment centers at home and abroad, demonstrating significant therapeutic potential. This article reviews the basic principle, development history, indications and contraindications of 90Y microsphere, as well as the specific applications in treatment of different types of metastatic liver cancers, aiming to provide references for further research and optimization of treatment strategies.
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publisher Shanghai Chinese Clinical Medicine Press Co., Ltd.
record_format Article
series Zhongguo Linchuang Yixue
spelling doaj-art-42899cb43b704d0e9f54025650e7caa32025-08-20T02:18:14ZengShanghai Chinese Clinical Medicine Press Co., Ltd.Zhongguo Linchuang Yixue1008-63582025-02-01321152310.12025/j.issn.1008-6358.2025.2024153320241533Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancerGuanxiang ZHUO0Linhe GAN1Jinfeng LIAN2Yilin WANG3Department of Hepatobiliary Surgery, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen 350003, Fujian, ChinaDepartment of Hepatobiliary Surgery, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen 350003, Fujian, ChinaDepartment of Hepatobiliary Surgery, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen 350003, Fujian, ChinaDepartment of Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, ChinaYttrium-90 microsphere selective internal radiation therapy (90Y-SIRT) has been widely used in the treatment of malignant liver cancers, and its safety and efficacy have been fully validated. As an important local therapeutic method, 90Y-SIRT has been utilized for the treatment of multiple metastatic liver cancers in many cancer diagnosis and treatment centers at home and abroad, demonstrating significant therapeutic potential. This article reviews the basic principle, development history, indications and contraindications of 90Y microsphere, as well as the specific applications in treatment of different types of metastatic liver cancers, aiming to provide references for further research and optimization of treatment strategies.https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20241533metastatic liver canceryttrium-90 microsphereselective internal radiation therapyinterventional therapy
spellingShingle Guanxiang ZHUO
Linhe GAN
Jinfeng LIAN
Yilin WANG
Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
Zhongguo Linchuang Yixue
metastatic liver cancer
yttrium-90 microsphere
selective internal radiation therapy
interventional therapy
title Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
title_full Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
title_fullStr Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
title_full_unstemmed Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
title_short Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer
title_sort application progress of yttrium 90 microsphere selective internal radiation therapy on metastatic liver cancer
topic metastatic liver cancer
yttrium-90 microsphere
selective internal radiation therapy
interventional therapy
url https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2025.20241533
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AT jinfenglian applicationprogressofyttrium90microsphereselectiveinternalradiationtherapyonmetastaticlivercancer
AT yilinwang applicationprogressofyttrium90microsphereselectiveinternalradiationtherapyonmetastaticlivercancer