Oocytes Quality Assessment—The Current Insight: A Systematic Review
An overall in vitro fertilization (IVF) outcome is dynamic. Good oocyte quality is important for achieving a better IVF pregnancy. Various methods have been used for OQ assessment (OQA). However, due to inconclusive evidence, one method’s superiority has not been proposed over others. Thus, OQA shou...
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MDPI AG
2024-11-01
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| author | Mohd Faizal Ahmad Marjanu Hikmah Elias Norazilah Mat Jin Muhammad Azrai Abu Saiful Effendi Syafruddin Ani Amelia Zainuddin Nao Suzuki Abdul Kadir Abdul Karim |
| author_facet | Mohd Faizal Ahmad Marjanu Hikmah Elias Norazilah Mat Jin Muhammad Azrai Abu Saiful Effendi Syafruddin Ani Amelia Zainuddin Nao Suzuki Abdul Kadir Abdul Karim |
| author_sort | Mohd Faizal Ahmad |
| collection | DOAJ |
| description | An overall in vitro fertilization (IVF) outcome is dynamic. Good oocyte quality is important for achieving a better IVF pregnancy. Various methods have been used for OQ assessment (OQA). However, due to inconclusive evidence, one method’s superiority has not been proposed over others. Thus, OQA should be consolidated based on the current evidence for this matter. Our study aims to summarize the current OQA used and compare their recommended methods. Our results revealed that the optimal OQA for cost-effectiveness and clinical implementation is still via morphological assessment. The current method most opted for is total oocyte scoring. Although other methods—follicular fluid evaluation, mitochondria spindle assessment, or live zona imaging—can be applied with better precision, due to cost, additional tools, and expertise, and they should cater to research purposes and selected centers. Our results added value as a current strategy for optimizing OQA in IVF practice, aiming at cost-effectiveness and reproducibility for better clinical implementation. |
| format | Article |
| id | doaj-art-427f8975356a433e92f29f57fb6b5b7f |
| institution | DOAJ |
| issn | 2079-7737 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj-art-427f8975356a433e92f29f57fb6b5b7f2025-08-20T02:53:27ZengMDPI AGBiology2079-77372024-11-01131297810.3390/biology13120978Oocytes Quality Assessment—The Current Insight: A Systematic ReviewMohd Faizal Ahmad0Marjanu Hikmah Elias1Norazilah Mat Jin2Muhammad Azrai Abu3Saiful Effendi Syafruddin4Ani Amelia Zainuddin5Nao Suzuki6Abdul Kadir Abdul Karim7Advanced Reproductive Centre (ARC) HCTM UKM, Department of Obstetrics & Gynecology, Faculty of Medicine, National University of Malaysia, Jalan Yaacob Latiff, Cheras, Kuala Lumpur 56000, MalaysiaFaculty of Medicine & Health Sciences, Universiti Sains Islam Malaysia, Nilai 71800, MalaysiaDepartment of Obstetrics & Gynecology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor Branch, Jalan Hospital, Sungai Buloh 47000, MalaysiaAdvanced Reproductive Centre (ARC) HCTM UKM, Department of Obstetrics & Gynecology, Faculty of Medicine, National University of Malaysia, Jalan Yaacob Latiff, Cheras, Kuala Lumpur 56000, MalaysiaMedical Molecular Biology Institute, National University of Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur 56000, MalaysiaAdvanced Reproductive Centre (ARC) HCTM UKM, Department of Obstetrics & Gynecology, Faculty of Medicine, National University of Malaysia, Jalan Yaacob Latiff, Cheras, Kuala Lumpur 56000, MalaysiaDepartment of Obstetrics & Gynecology, St Marianna School of Medicine, Kawasaki 216-0015, Kanagawa, JapanAdvanced Reproductive Centre (ARC) HCTM UKM, Department of Obstetrics & Gynecology, Faculty of Medicine, National University of Malaysia, Jalan Yaacob Latiff, Cheras, Kuala Lumpur 56000, MalaysiaAn overall in vitro fertilization (IVF) outcome is dynamic. Good oocyte quality is important for achieving a better IVF pregnancy. Various methods have been used for OQ assessment (OQA). However, due to inconclusive evidence, one method’s superiority has not been proposed over others. Thus, OQA should be consolidated based on the current evidence for this matter. Our study aims to summarize the current OQA used and compare their recommended methods. Our results revealed that the optimal OQA for cost-effectiveness and clinical implementation is still via morphological assessment. The current method most opted for is total oocyte scoring. Although other methods—follicular fluid evaluation, mitochondria spindle assessment, or live zona imaging—can be applied with better precision, due to cost, additional tools, and expertise, and they should cater to research purposes and selected centers. Our results added value as a current strategy for optimizing OQA in IVF practice, aiming at cost-effectiveness and reproducibility for better clinical implementation.https://www.mdpi.com/2079-7737/13/12/978oocytes quality assessmentoocytes morphologyin vitro fertilization (IVF) |
| spellingShingle | Mohd Faizal Ahmad Marjanu Hikmah Elias Norazilah Mat Jin Muhammad Azrai Abu Saiful Effendi Syafruddin Ani Amelia Zainuddin Nao Suzuki Abdul Kadir Abdul Karim Oocytes Quality Assessment—The Current Insight: A Systematic Review Biology oocytes quality assessment oocytes morphology in vitro fertilization (IVF) |
| title | Oocytes Quality Assessment—The Current Insight: A Systematic Review |
| title_full | Oocytes Quality Assessment—The Current Insight: A Systematic Review |
| title_fullStr | Oocytes Quality Assessment—The Current Insight: A Systematic Review |
| title_full_unstemmed | Oocytes Quality Assessment—The Current Insight: A Systematic Review |
| title_short | Oocytes Quality Assessment—The Current Insight: A Systematic Review |
| title_sort | oocytes quality assessment the current insight a systematic review |
| topic | oocytes quality assessment oocytes morphology in vitro fertilization (IVF) |
| url | https://www.mdpi.com/2079-7737/13/12/978 |
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