Genome Editing as a Vehicle to Drive Successful Chimeric Antigen Receptor T Cell Therapies to the Clinic
Chimeric antigen receptor (CAR) T cells have emerged as an effective therapy for patients with relapsed and refractory haematological malignancies. However, there are many challenges preventing clinical efficacy and thus broader translation of this approach. These hurdles include poor autologous T...
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| Main Authors: | Caitlin R Hopkins, Joseph A Fraietta |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Medical Journal
2021-12-01
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| Series: | European Medical Journal |
| Online Access: | https://www.emjreviews.com/hematology/article/genome-editing-as-a-vehicle-to-drive-successful-chimeric-antigen-receptor-t-cell-therapies-to-the-clinic/ |
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