Dealing with Pheochromocytoma during the First Trimester of Pregnancy

Purpose. Pheochromocytoma in association with pregnancy is a very rare, without specific symptoms, life-threatening condition, increasing both maternal and fetal mortality up to 50%. The present paper illustrates the case of a pregnant woman, diagnosed with pheochromocytoma, aiming to demonstrate an...

Full description

Saved in:
Bibliographic Details
Main Authors: Konstantinos Kiroplastis, Apostolos Kambaroudis, Apostolos Andronikou, Andromachi Reklou, Dimitris Kokkonis, Panagiotis Petras, Apostolos Mamopoulos, Eudokia Anagnostara, Charalampos Spyridis
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2015/439127
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832554144691388416
author Konstantinos Kiroplastis
Apostolos Kambaroudis
Apostolos Andronikou
Andromachi Reklou
Dimitris Kokkonis
Panagiotis Petras
Apostolos Mamopoulos
Eudokia Anagnostara
Charalampos Spyridis
author_facet Konstantinos Kiroplastis
Apostolos Kambaroudis
Apostolos Andronikou
Andromachi Reklou
Dimitris Kokkonis
Panagiotis Petras
Apostolos Mamopoulos
Eudokia Anagnostara
Charalampos Spyridis
author_sort Konstantinos Kiroplastis
collection DOAJ
description Purpose. Pheochromocytoma in association with pregnancy is a very rare, without specific symptoms, life-threatening condition, increasing both maternal and fetal mortality up to 50%. The present paper illustrates the case of a pregnant woman, diagnosed with pheochromocytoma, aiming to demonstrate and discuss the difficulties that arouse during the diagnosis and the problems concerning the treatment. Patient. A 34-year-old woman, in the 9th week of pregnancy, complained for headache, sweating, and a feeling of heavy weight on the right renal area. A tumor of 10 cm diameter at the site of the right adrenal was found. Twenty-four-hour urine catecholamine and VMA excretion levels were well raised. Results. Multidisciplinary approach treated the patient conservatively. Surgical resection of the tumor was performed after the 14th week of pregnancy at the completion of organogenesis. Neither postoperative complications occurred nor hypertension relapse was recorded. The fetus was delivered without complications at the 36th week. Conclusions. There are no consensus and guidelines for treating pheochromocytoma during pregnancy, especially when it is diagnosed in the first trimester. The week of pregnancy and a multidisciplinary approach will determine whether the pregnancy should be continued or not, as well as the time and the approach of surgical treatment.
format Article
id doaj-art-42609877fb9a4e89bde715a3a55624ce
institution Kabale University
issn 2090-6684
2090-6692
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Obstetrics and Gynecology
spelling doaj-art-42609877fb9a4e89bde715a3a55624ce2025-02-03T05:52:11ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/439127439127Dealing with Pheochromocytoma during the First Trimester of PregnancyKonstantinos Kiroplastis0Apostolos Kambaroudis1Apostolos Andronikou2Andromachi Reklou3Dimitris Kokkonis4Panagiotis Petras5Apostolos Mamopoulos6Eudokia Anagnostara7Charalampos Spyridis8Fifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceFifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceFifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceSecond Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceFifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceFifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceThird Obstetric Department, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceAnesthesiology Department, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreeceFifth Surgical Department, Aristotle University of Thessaloniki, Hippokratio General Hospital of Thessaloniki, Konstantinoupoleos 49 Street, 54642 Thessaloniki, GreecePurpose. Pheochromocytoma in association with pregnancy is a very rare, without specific symptoms, life-threatening condition, increasing both maternal and fetal mortality up to 50%. The present paper illustrates the case of a pregnant woman, diagnosed with pheochromocytoma, aiming to demonstrate and discuss the difficulties that arouse during the diagnosis and the problems concerning the treatment. Patient. A 34-year-old woman, in the 9th week of pregnancy, complained for headache, sweating, and a feeling of heavy weight on the right renal area. A tumor of 10 cm diameter at the site of the right adrenal was found. Twenty-four-hour urine catecholamine and VMA excretion levels were well raised. Results. Multidisciplinary approach treated the patient conservatively. Surgical resection of the tumor was performed after the 14th week of pregnancy at the completion of organogenesis. Neither postoperative complications occurred nor hypertension relapse was recorded. The fetus was delivered without complications at the 36th week. Conclusions. There are no consensus and guidelines for treating pheochromocytoma during pregnancy, especially when it is diagnosed in the first trimester. The week of pregnancy and a multidisciplinary approach will determine whether the pregnancy should be continued or not, as well as the time and the approach of surgical treatment.http://dx.doi.org/10.1155/2015/439127
spellingShingle Konstantinos Kiroplastis
Apostolos Kambaroudis
Apostolos Andronikou
Andromachi Reklou
Dimitris Kokkonis
Panagiotis Petras
Apostolos Mamopoulos
Eudokia Anagnostara
Charalampos Spyridis
Dealing with Pheochromocytoma during the First Trimester of Pregnancy
Case Reports in Obstetrics and Gynecology
title Dealing with Pheochromocytoma during the First Trimester of Pregnancy
title_full Dealing with Pheochromocytoma during the First Trimester of Pregnancy
title_fullStr Dealing with Pheochromocytoma during the First Trimester of Pregnancy
title_full_unstemmed Dealing with Pheochromocytoma during the First Trimester of Pregnancy
title_short Dealing with Pheochromocytoma during the First Trimester of Pregnancy
title_sort dealing with pheochromocytoma during the first trimester of pregnancy
url http://dx.doi.org/10.1155/2015/439127
work_keys_str_mv AT konstantinoskiroplastis dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT apostoloskambaroudis dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT apostolosandronikou dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT andromachireklou dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT dimitriskokkonis dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT panagiotispetras dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT apostolosmamopoulos dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT eudokiaanagnostara dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy
AT charalamposspyridis dealingwithpheochromocytomaduringthefirsttrimesterofpregnancy