AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices

Abstract Cognitive decline affects over 50 million people globally, with prevalence expected to triple by 2050. AI-driven digital therapeutics—encompassing mobile applications, virtual reality, and wearable devices—offer transformative opportunities for cognitive rehabilitation by leveraging adaptiv...

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Main Author: Dian Jiao
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Artificial Intelligence
Subjects:
Online Access:https://doi.org/10.1007/s44163-025-00325-6
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author Dian Jiao
author_facet Dian Jiao
author_sort Dian Jiao
collection DOAJ
description Abstract Cognitive decline affects over 50 million people globally, with prevalence expected to triple by 2050. AI-driven digital therapeutics—encompassing mobile applications, virtual reality, and wearable devices—offer transformative opportunities for cognitive rehabilitation by leveraging adaptive algorithms and real-time feedback to deliver personalized interventions. This review systematically examines these technologies, highlighting their unique strengths in enhancing cognitive functions while acknowledging their limitations: mobile applications face retention challenges despite demonstrated effectiveness; virtual reality provides immersive environments that enhance motivation and ecological validity yet struggles with usability issues; and wearable devices offer continuous monitoring but encounter data integration and compliance difficulties. The integration of artificial intelligence enables dynamic personalization, predictive analytics, and multi-modal data fusion, creating unified therapeutic ecosystems that enhance outcomes despite persistent challenges related to data security, ethics, and algorithmic transparency. By addressing these limitations and leveraging AI's adaptive potential, digital therapeutics can revolutionize cognitive rehabilitation, improving health outcomes and quality of life for individuals with cognitive impairments worldwide.
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spelling doaj-art-4260792cf74f474e9d1cd8d99fa7e6882025-08-20T03:08:43ZengSpringerDiscover Artificial Intelligence2731-08092025-05-015111310.1007/s44163-025-00325-6AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devicesDian Jiao0Institute of Psychiatry, Psychology & Neuroscience, King’s College LondonAbstract Cognitive decline affects over 50 million people globally, with prevalence expected to triple by 2050. AI-driven digital therapeutics—encompassing mobile applications, virtual reality, and wearable devices—offer transformative opportunities for cognitive rehabilitation by leveraging adaptive algorithms and real-time feedback to deliver personalized interventions. This review systematically examines these technologies, highlighting their unique strengths in enhancing cognitive functions while acknowledging their limitations: mobile applications face retention challenges despite demonstrated effectiveness; virtual reality provides immersive environments that enhance motivation and ecological validity yet struggles with usability issues; and wearable devices offer continuous monitoring but encounter data integration and compliance difficulties. The integration of artificial intelligence enables dynamic personalization, predictive analytics, and multi-modal data fusion, creating unified therapeutic ecosystems that enhance outcomes despite persistent challenges related to data security, ethics, and algorithmic transparency. By addressing these limitations and leveraging AI's adaptive potential, digital therapeutics can revolutionize cognitive rehabilitation, improving health outcomes and quality of life for individuals with cognitive impairments worldwide.https://doi.org/10.1007/s44163-025-00325-6Digital therapeuticsCognitive impairmentMobile applicationsVirtual realityArtificial intelligenceCognitive rehabilitation
spellingShingle Dian Jiao
AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
Discover Artificial Intelligence
Digital therapeutics
Cognitive impairment
Mobile applications
Virtual reality
Artificial intelligence
Cognitive rehabilitation
title AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
title_full AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
title_fullStr AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
title_full_unstemmed AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
title_short AI-enhanced digital therapeutics for cognitive impairment: integrating mobile applications, virtual reality, and wearable devices
title_sort ai enhanced digital therapeutics for cognitive impairment integrating mobile applications virtual reality and wearable devices
topic Digital therapeutics
Cognitive impairment
Mobile applications
Virtual reality
Artificial intelligence
Cognitive rehabilitation
url https://doi.org/10.1007/s44163-025-00325-6
work_keys_str_mv AT dianjiao aienhanceddigitaltherapeuticsforcognitiveimpairmentintegratingmobileapplicationsvirtualrealityandwearabledevices