Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia
Abstract Traditional dementia-prevention programs have limited accessibility and lack continuous monitoring, making sustained cognitive and emotional support challenging. This study evaluated the effects of artificial intelligence (AI) care calls on the cognitive function and depression of community...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-12895-7 |
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| author | Sungwoo Kang Yunjin Lee Nayoung Kim Sang-Houn Ok Pilsu Kim Ok-Hyun Park Da-Mi Kim Yongwoo Jang Hee-Jin Kim |
| author_facet | Sungwoo Kang Yunjin Lee Nayoung Kim Sang-Houn Ok Pilsu Kim Ok-Hyun Park Da-Mi Kim Yongwoo Jang Hee-Jin Kim |
| author_sort | Sungwoo Kang |
| collection | DOAJ |
| description | Abstract Traditional dementia-prevention programs have limited accessibility and lack continuous monitoring, making sustained cognitive and emotional support challenging. This study evaluated the effects of artificial intelligence (AI) care calls on the cognitive function and depression of community-dwelling individuals. Eighty participants with dementia received AI care calls twice weekly from April 23 to November 28, 2024, with 63 calls per participant. The AI care call provided emotional support and cognitive engagement. Cognitive function (attention, memory, and language) and geriatric depression scale (GDS) scores were assessed before and after the intervention. The Wilcoxon signed-rank test was used to compare the pre- and post-intervention scores. General linear models were used to examine the effects of age, sex, and education on changes in clinical measures while controlling for baseline clinical scores. After the AI care call intervention, GDS scores decreased significantly, while memory scores increased significantly. An interaction effect between age and sex was observed in attention and memory score changes, with females showing greater memory improvement and maintenance of attention scores, whereas males experienced a decline in attention scores with no significant change in memory. Additionally, an interaction effect between age and education was observed in the GDS and attention score changes, suggesting that higher education was associated with a protective effect against the worsening of these symptoms following the AI care call intervention. AI care calls may help reduce depression and improve memory function in community-dwelling individuals. The differential effects of sex and education suggest that these factors affect the effectiveness of interventions. |
| format | Article |
| id | doaj-art-425aa7246bdd4842be9f774472df8313 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-425aa7246bdd4842be9f774472df83132025-08-20T03:43:11ZengNature PortfolioScientific Reports2045-23222025-07-011511810.1038/s41598-025-12895-7Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementiaSungwoo Kang0Yunjin Lee1Nayoung Kim2Sang-Houn Ok3Pilsu Kim4Ok-Hyun Park5Da-Mi Kim6Yongwoo Jang7Hee-Jin Kim8Department of Neurology, Hanyang University College of MedicineDepartment of Medical and Digital Engineering, Hanyang UniversityDepartment of Medical and Digital Engineering, Hanyang UniversityNAVER CloudNAVER CloudSeongdong-gu Dementia Safety CenterSeongdong-gu Dementia Safety CenterDepartment of Pharmacology, Hanyang University College of MedicineDepartment of Neurology, Hanyang University College of MedicineAbstract Traditional dementia-prevention programs have limited accessibility and lack continuous monitoring, making sustained cognitive and emotional support challenging. This study evaluated the effects of artificial intelligence (AI) care calls on the cognitive function and depression of community-dwelling individuals. Eighty participants with dementia received AI care calls twice weekly from April 23 to November 28, 2024, with 63 calls per participant. The AI care call provided emotional support and cognitive engagement. Cognitive function (attention, memory, and language) and geriatric depression scale (GDS) scores were assessed before and after the intervention. The Wilcoxon signed-rank test was used to compare the pre- and post-intervention scores. General linear models were used to examine the effects of age, sex, and education on changes in clinical measures while controlling for baseline clinical scores. After the AI care call intervention, GDS scores decreased significantly, while memory scores increased significantly. An interaction effect between age and sex was observed in attention and memory score changes, with females showing greater memory improvement and maintenance of attention scores, whereas males experienced a decline in attention scores with no significant change in memory. Additionally, an interaction effect between age and education was observed in the GDS and attention score changes, suggesting that higher education was associated with a protective effect against the worsening of these symptoms following the AI care call intervention. AI care calls may help reduce depression and improve memory function in community-dwelling individuals. The differential effects of sex and education suggest that these factors affect the effectiveness of interventions.https://doi.org/10.1038/s41598-025-12895-7Artificial intelligenceLarge language modelInterventionCognitionDepression |
| spellingShingle | Sungwoo Kang Yunjin Lee Nayoung Kim Sang-Houn Ok Pilsu Kim Ok-Hyun Park Da-Mi Kim Yongwoo Jang Hee-Jin Kim Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia Scientific Reports Artificial intelligence Large language model Intervention Cognition Depression |
| title | Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| title_full | Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| title_fullStr | Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| title_full_unstemmed | Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| title_short | Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| title_sort | beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia |
| topic | Artificial intelligence Large language model Intervention Cognition Depression |
| url | https://doi.org/10.1038/s41598-025-12895-7 |
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