Causal impact of elevated body mass index on diabetic kidney disease: an integrated Mendelian randomization and Global Burden of Disease Study 2021 analysis

Causal impact of elevated body mass index on diabetic kidney disease: an integrated Mendelian randomization and Global Burden of Disease Study 2021 analysis

Background Elevated body mass index (BMI) has been implicated in the pathogenesis of diabetic kidney disease among patients with type 2 diabetes mellitus (T2DKD). However, establishing a causal relationship and quantifying the resultant global health impact remain challenging.Methods A two-sample Me...

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Bibliographic Details
Main Authors: Ye-xin Chen, Dong-sen Hu, Mao-xuan Lin, Zi-heng Gao, Han-zhang Hong, Yu-xin Hu, Ling-zi Yao, Gai-wen Cui, Lin Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Mendelian Randomization
Global Burden of Disease Study 2021
diabetic kidney disease
elevated body mass index
type 2 diabetes mellitus
chronic kidney disease
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2472981
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