Single-nucleus and spatial transcriptomics identify brain landscape of gene regulatory networks associated with behavioral maturation in honeybees

Single-nucleus and spatial transcriptomics identify brain landscape of gene regulatory networks associated with behavioral maturation in honeybees

Abstract Animal behavior is linked to the gene regulatory network (GRN) coordinating gene expression in the brain. Eusocial honeybees, with their natural behavioral plasticity, provide an excellent model for exploring the connection between brain activity and behavior. Using single-nucleus RNA seque...

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Main Authors: Xiaohuan Mu, Zijing Zhang, Qun Liu, Jie Ma, Yating Qin, Haoyu Lang, Yingying Zhang, Nannan Zhang, Qunfei Guo, Pei Zhang, Denghui Li, Ruihua Zhang, Qianyue Ji, Aijun Jiang, Yang Wang, Shanshan Pan, Xiawei Liu, Xuemei Liu, Jiahui Sun, Yan Liu, Hao Chen, Li Zheng, Liang Meng, Haorong Lu, He Zhang, Yifan Zhai, Qiye Li, Junnian Liu, Huanming Yang, Jian Wang, Xiaosong Hu, Xun Xu, Shanshan Liu, Hao Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58614-8
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