Severe anaemia in people with HIV: demographic, clinical and renal correlates
Abstract Objective This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV. Methods We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia...
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BMC
2025-02-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-025-07100-x |
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| author | Kingsley Kamvuma Sody Munsaka Sepiso K. Masenga John Amos Mulemena Christopher Newton Phiri Michelo Miyoba Benson M. Hamooya |
| author_facet | Kingsley Kamvuma Sody Munsaka Sepiso K. Masenga John Amos Mulemena Christopher Newton Phiri Michelo Miyoba Benson M. Hamooya |
| author_sort | Kingsley Kamvuma |
| collection | DOAJ |
| description | Abstract Objective This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV. Methods We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation. Results The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053–0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14–126.6), albumin (AOR: 0.93 95% CI: 0.88–0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03). |
| format | Article |
| id | doaj-art-4243ecf134d7411fa150cf094da04d99 |
| institution | Kabale University |
| issn | 1756-0500 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj-art-4243ecf134d7411fa150cf094da04d992025-02-09T12:09:55ZengBMCBMC Research Notes1756-05002025-02-011811610.1186/s13104-025-07100-xSevere anaemia in people with HIV: demographic, clinical and renal correlatesKingsley Kamvuma0Sody Munsaka1Sepiso K. Masenga2John Amos Mulemena3Christopher Newton Phiri4Michelo Miyoba5Benson M. Hamooya6HAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityDepartment of Biomedical Sciences, University of Zambia of Health Science and MedicineHAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityHAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityHAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityHAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityHAND Research Group, School of Medicine and Health Sciences, Department of Pathology and Microbiology, Mulungush UniversityAbstract Objective This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV. Methods We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation. Results The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053–0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14–126.6), albumin (AOR: 0.93 95% CI: 0.88–0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).https://doi.org/10.1186/s13104-025-07100-xSevere anaemiaRenal insufficiencyPLWHART |
| spellingShingle | Kingsley Kamvuma Sody Munsaka Sepiso K. Masenga John Amos Mulemena Christopher Newton Phiri Michelo Miyoba Benson M. Hamooya Severe anaemia in people with HIV: demographic, clinical and renal correlates BMC Research Notes Severe anaemia Renal insufficiency PLWH ART |
| title | Severe anaemia in people with HIV: demographic, clinical and renal correlates |
| title_full | Severe anaemia in people with HIV: demographic, clinical and renal correlates |
| title_fullStr | Severe anaemia in people with HIV: demographic, clinical and renal correlates |
| title_full_unstemmed | Severe anaemia in people with HIV: demographic, clinical and renal correlates |
| title_short | Severe anaemia in people with HIV: demographic, clinical and renal correlates |
| title_sort | severe anaemia in people with hiv demographic clinical and renal correlates |
| topic | Severe anaemia Renal insufficiency PLWH ART |
| url | https://doi.org/10.1186/s13104-025-07100-x |
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