Severe anaemia in people with HIV: demographic, clinical and renal correlates

Abstract Objective This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV. Methods We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia...

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Main Authors: Kingsley Kamvuma, Sody Munsaka, Sepiso K. Masenga, John Amos Mulemena, Christopher Newton Phiri, Michelo Miyoba, Benson M. Hamooya
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Research Notes
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Online Access:https://doi.org/10.1186/s13104-025-07100-x
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Summary:Abstract Objective This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV. Methods We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation. Results The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053–0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14–126.6), albumin (AOR: 0.93 95% CI: 0.88–0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).
ISSN:1756-0500