MiR-383-5p promotes schistosomiasis-induced liver fibrosis by targeting peroxiredoxin-3

MiR-383-5p promotes schistosomiasis-induced liver fibrosis by targeting peroxiredoxin-3

Abstract Background Schistosomiasis-induced liver fibrosis, a major complication of infection, arises primarily from the host immune response to schistosome eggs. The mechanisms underlying the development of liver fibrosis remain unclear, but microRNAs (miRNAs) are thought to play a crucial role in...

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Main Authors: Yi-Xin Li, Xin-Yue Zhang, Ju-Lu Lu, Ying-Ying Yang, Cong-Jin Mei, Pan-Pan Dong, Chuan-Xin Yu, Jian-Feng Zhang, Chun-Rong Xiong, Li-Jun Song, Kun Yang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Parasites & Vectors
Subjects:
miR-383-5p
PRDX3
ROS
Liver fibrosis
Schistosomiasis
Online Access:https://doi.org/10.1186/s13071-025-06824-w
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