Stem cells in gastroenterology: prospects and problems
The aim of review. To generalize cumulative data on the role of stem cells (SC) in treatment of gastroenterological diseases.Original positions. Cell-based treatment is rather new and, probably, promising trend in treatment of many severe diseases in which traditional methods fail to achieve due res...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2011-12-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1469 |
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| _version_ | 1823860188026765312 |
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| author | A. O. Buyeverov V. T. Ivashkin |
| author_facet | A. O. Buyeverov V. T. Ivashkin |
| author_sort | A. O. Buyeverov |
| collection | DOAJ |
| description | The aim of review. To generalize cumulative data on the role of stem cells (SC) in treatment of gastroenterological diseases.Original positions. Cell-based treatment is rather new and, probably, promising trend in treatment of many severe diseases in which traditional methods fail to achieve due results. In therapeutic aspect of gastrointestinal and liver diseases inflammatory bowel diseases, colorectal cancer and decompensated liver cirrhosis seem to be most perspective at the present stage. At the same time clinical application of SC is associated to array of serious problems: immune rejection and «graft-versus-host» response, neoplastic transformation as well as ethical and religious restrictions. Conclusion. Application SC in clinical gastroenterology is premature today. Their efficacy and safety requires confirmation in multicenter randomized trials. |
| format | Article |
| id | doaj-art-4238fe5499414c6fa4268f43225ae9bd |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2011-12-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-4238fe5499414c6fa4268f43225ae9bd2025-02-10T16:14:31ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732011-12-01216411993Stem cells in gastroenterology: prospects and problemsA. O. Buyeverov0V. T. Ivashkin1Государственное образовательное учреждение высшего профессионального образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минзравсоцразвития РФГосударственное образовательное учреждение высшего профессионального образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минзравсоцразвития РФThe aim of review. To generalize cumulative data on the role of stem cells (SC) in treatment of gastroenterological diseases.Original positions. Cell-based treatment is rather new and, probably, promising trend in treatment of many severe diseases in which traditional methods fail to achieve due results. In therapeutic aspect of gastrointestinal and liver diseases inflammatory bowel diseases, colorectal cancer and decompensated liver cirrhosis seem to be most perspective at the present stage. At the same time clinical application of SC is associated to array of serious problems: immune rejection and «graft-versus-host» response, neoplastic transformation as well as ethical and religious restrictions. Conclusion. Application SC in clinical gastroenterology is premature today. Their efficacy and safety requires confirmation in multicenter randomized trials.https://www.gastro-j.ru/jour/article/view/1469stem cellsinflammatory bowel diseasescolorectal cancerliver cirrhosistreatment |
| spellingShingle | A. O. Buyeverov V. T. Ivashkin Stem cells in gastroenterology: prospects and problems Российский журнал гастроэнтерологии, гепатологии, колопроктологии stem cells inflammatory bowel diseases colorectal cancer liver cirrhosis treatment |
| title | Stem cells in gastroenterology: prospects and problems |
| title_full | Stem cells in gastroenterology: prospects and problems |
| title_fullStr | Stem cells in gastroenterology: prospects and problems |
| title_full_unstemmed | Stem cells in gastroenterology: prospects and problems |
| title_short | Stem cells in gastroenterology: prospects and problems |
| title_sort | stem cells in gastroenterology prospects and problems |
| topic | stem cells inflammatory bowel diseases colorectal cancer liver cirrhosis treatment |
| url | https://www.gastro-j.ru/jour/article/view/1469 |
| work_keys_str_mv | AT aobuyeverov stemcellsingastroenterologyprospectsandproblems AT vtivashkin stemcellsingastroenterologyprospectsandproblems |