One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases
ABSTRACT Background Surgical intervention remains the primary therapeutic modality for managing multiple pulmonary nodules. However, in cases with bilateral pulmonary nodules, one‐stage bilateral resection is discouraged due to tumor aggressiveness and surgical invasiveness. In light of this, we inv...
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Wiley
2025-03-01
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| Series: | Thoracic Cancer |
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| Online Access: | https://doi.org/10.1111/1759-7714.70053 |
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| author | Zhen Wang Zhaolei You Yingjian Song Hua Ji Guodong Jiang Xiaokun Bu Jingyu Zhang Tengfei Yi Jian Fang Xiaofeng Yu |
| author_facet | Zhen Wang Zhaolei You Yingjian Song Hua Ji Guodong Jiang Xiaokun Bu Jingyu Zhang Tengfei Yi Jian Fang Xiaofeng Yu |
| author_sort | Zhen Wang |
| collection | DOAJ |
| description | ABSTRACT Background Surgical intervention remains the primary therapeutic modality for managing multiple pulmonary nodules. However, in cases with bilateral pulmonary nodules, one‐stage bilateral resection is discouraged due to tumor aggressiveness and surgical invasiveness. In light of this, we investigated an innovative approach, termed one‐stage bilateral pulmonary nodule resection via unilateral thoracic cavity access. Methods From July 2022 to September 2024, a cohort of 12 patients with bilateral pulmonary nodules were enrolled in this study. This technique involves initial unilateral transcostal incision for segmental or lobectomy of a nodule on one side, followed by bilateral mediastinal pleura incision through the anterior mediastinum, facilitating subsequent wedge resection of the contralateral nodule. Clinical and pathological data, along with perioperative imaging findings and follow‐up information, were systematically collected and subjected to a comprehensive retrospective analysis. Results A total of 25 nodules were resected from 12 patients. Regarding surgical approaches, nine patients underwent right thoracic incision, while three patients underwent left thoracic incision. Intraoperatively, seven patients received bilateral wedge resections, whereas five patients underwent segmentectomy on one side combined with wedge resection on the contralateral side. R0 resection of the contralateral nodules was successfully achieved during the procedures. The average distance between the surgical margin and the contralateral nodules was 12.5 mm, ranging from 5 mm to 25 mm. Of the 12 patients, one (Patient 6) was lost to follow‐up, while the remaining 11 patients underwent postoperative chest CT examinations. The median follow‐up duration for these 11 patients was 105 days (range: 36–857 days). No evidence of bilateral pleural effusion or tumor recurrence was detected on follow‐up chest CT scans. Conclusions This study offers the potential to concurrently address bilateral pulmonary nodules, thereby sparing patients from the need for a subsequent hospitalization for surgical intervention. |
| format | Article |
| id | doaj-art-4231dc5d4af44ec0b81b9bcafadbde2d |
| institution | Kabale University |
| issn | 1759-7706 1759-7714 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj-art-4231dc5d4af44ec0b81b9bcafadbde2d2025-08-20T03:40:54ZengWileyThoracic Cancer1759-77061759-77142025-03-01166n/an/a10.1111/1759-7714.70053One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 CasesZhen Wang0Zhaolei You1Yingjian Song2Hua Ji3Guodong Jiang4Xiaokun Bu5Jingyu Zhang6Tengfei Yi7Jian Fang8Xiaofeng Yu9Department of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Cardiothoracic Surgery The People's Hospital of Zhaoyuan City Yantai People's Republic of ChinaDepartment of Cardiothoracic Surgery Yantai Yeda Hospital Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaDepartment of Thoracic Surgery Yantai Yuhuangding Hospital, Qingdao University Yantai People's Republic of ChinaABSTRACT Background Surgical intervention remains the primary therapeutic modality for managing multiple pulmonary nodules. However, in cases with bilateral pulmonary nodules, one‐stage bilateral resection is discouraged due to tumor aggressiveness and surgical invasiveness. In light of this, we investigated an innovative approach, termed one‐stage bilateral pulmonary nodule resection via unilateral thoracic cavity access. Methods From July 2022 to September 2024, a cohort of 12 patients with bilateral pulmonary nodules were enrolled in this study. This technique involves initial unilateral transcostal incision for segmental or lobectomy of a nodule on one side, followed by bilateral mediastinal pleura incision through the anterior mediastinum, facilitating subsequent wedge resection of the contralateral nodule. Clinical and pathological data, along with perioperative imaging findings and follow‐up information, were systematically collected and subjected to a comprehensive retrospective analysis. Results A total of 25 nodules were resected from 12 patients. Regarding surgical approaches, nine patients underwent right thoracic incision, while three patients underwent left thoracic incision. Intraoperatively, seven patients received bilateral wedge resections, whereas five patients underwent segmentectomy on one side combined with wedge resection on the contralateral side. R0 resection of the contralateral nodules was successfully achieved during the procedures. The average distance between the surgical margin and the contralateral nodules was 12.5 mm, ranging from 5 mm to 25 mm. Of the 12 patients, one (Patient 6) was lost to follow‐up, while the remaining 11 patients underwent postoperative chest CT examinations. The median follow‐up duration for these 11 patients was 105 days (range: 36–857 days). No evidence of bilateral pleural effusion or tumor recurrence was detected on follow‐up chest CT scans. Conclusions This study offers the potential to concurrently address bilateral pulmonary nodules, thereby sparing patients from the need for a subsequent hospitalization for surgical intervention.https://doi.org/10.1111/1759-7714.70053bilateral pulmonary nodulesone‐stage resectionunilateral transcostal incision |
| spellingShingle | Zhen Wang Zhaolei You Yingjian Song Hua Ji Guodong Jiang Xiaokun Bu Jingyu Zhang Tengfei Yi Jian Fang Xiaofeng Yu One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases Thoracic Cancer bilateral pulmonary nodules one‐stage resection unilateral transcostal incision |
| title | One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases |
| title_full | One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases |
| title_fullStr | One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases |
| title_full_unstemmed | One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases |
| title_short | One‐Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single‐Center Experience of 12 Cases |
| title_sort | one stage bilateral pulmonary nodule resection via unilateral thoracic cavity access a single center experience of 12 cases |
| topic | bilateral pulmonary nodules one‐stage resection unilateral transcostal incision |
| url | https://doi.org/10.1111/1759-7714.70053 |
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