Adjuvant systemic therapy in melanoma: Relative versus absolute benefit; the number needed to treat (NNT) versus the number needed to harm (NNH)?

Adjuvant systemic therapy in melanoma: Relative versus absolute benefit; the number needed to treat (NNT) versus the number needed to harm (NNH)?

Adjuvant (ADJ) systemic therapy has transformed melanoma treatment during the past decade. There are, however, still important unanswered questions that lead to debates on the utility and place of ADJ therapy for melanoma. When ADJ trials are reported, they present a hazard ratio with a significant...

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Bibliographic Details
Main Authors: Alexander C.J. van Akkooi, Mario Mandala, Paul Nathan, Andrew Haydon, Michael Postow, Piotr Rutkowski
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:EJC Skin Cancer
Subjects:
Melanoma
Adjuvant
Immunotherapy
BRAF
Targeted therapy
Number needed to treat
Online Access:http://www.sciencedirect.com/science/article/pii/S2772611824000053
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