Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine

The objective of this study was to describe the epidemiology, clinical characteristics, microbiology and outcomes of patients of all ages with Streptococcus pneumoniae meningitis between 2000 and 2004; two years pre- and postintroduction of an S pneumoniae 7-valent conjugate vaccine program in Alber...

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Main Authors: Jennie Johnstone, Gregory J. Tyrrell, Thomas J. Marrie, Sipi Garg, James D. Kellner, the Streptococcus pneumoniae Alberta Team (SPAT) group
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2011/179170
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author Jennie Johnstone
Gregory J. Tyrrell
Thomas J. Marrie
Sipi Garg
James D. Kellner
the Streptococcus pneumoniae Alberta Team (SPAT) group
author_facet Jennie Johnstone
Gregory J. Tyrrell
Thomas J. Marrie
Sipi Garg
James D. Kellner
the Streptococcus pneumoniae Alberta Team (SPAT) group
author_sort Jennie Johnstone
collection DOAJ
description The objective of this study was to describe the epidemiology, clinical characteristics, microbiology and outcomes of patients of all ages with Streptococcus pneumoniae meningitis between 2000 and 2004; two years pre- and postintroduction of an S pneumoniae 7-valent conjugate vaccine program in Alberta in children younger than two years of age. The high mortality rate associated with S pneumoniae meningitis, despite appropriate therapy, suggests that prevention of S pneumoniae meningitis is critical. Despite implementation of a PCV-7 program in Alberta, rates of S pneumoniae meningitis in children younger than two years of age is still high. Thus, continued research into safe and efficacious vaccines covering a broader range of S pneumoniae serotypes is necessary.
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-41fce0e6e30944b79fd8d6ab0963cec52025-08-20T02:39:16ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322011-01-0122413714110.1155/2011/179170Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccineJennie Johnstone0Gregory J. Tyrrell1Thomas J. Marrie2Sipi Garg3James D. Kellner4the Streptococcus pneumoniae Alberta Team (SPAT) group5Department of Medicine, McMaster University, Hamilton, Ontario, CanadaLaboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, CanadaDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, CanadaThe Epidemiology Coordinating and Research (EPICORE) Centre, University of Alberta, Edmonton, CanadaDepartment of Pediatrics, University of Calgary, Calgary, Alberta, CanadaDepartment of Medicine, McMaster University, Hamilton, Ontario, CanadaThe objective of this study was to describe the epidemiology, clinical characteristics, microbiology and outcomes of patients of all ages with Streptococcus pneumoniae meningitis between 2000 and 2004; two years pre- and postintroduction of an S pneumoniae 7-valent conjugate vaccine program in Alberta in children younger than two years of age. The high mortality rate associated with S pneumoniae meningitis, despite appropriate therapy, suggests that prevention of S pneumoniae meningitis is critical. Despite implementation of a PCV-7 program in Alberta, rates of S pneumoniae meningitis in children younger than two years of age is still high. Thus, continued research into safe and efficacious vaccines covering a broader range of S pneumoniae serotypes is necessary.http://dx.doi.org/10.1155/2011/179170
spellingShingle Jennie Johnstone
Gregory J. Tyrrell
Thomas J. Marrie
Sipi Garg
James D. Kellner
the Streptococcus pneumoniae Alberta Team (SPAT) group
Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
Canadian Journal of Infectious Diseases and Medical Microbiology
title Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
title_full Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
title_fullStr Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
title_full_unstemmed Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
title_short Streptococcus pneumoniae meningitis in Alberta pre- and postintroduction of the 7-valent pneumococcal conjugate vaccine
title_sort streptococcus pneumoniae meningitis in alberta pre and postintroduction of the 7 valent pneumococcal conjugate vaccine
url http://dx.doi.org/10.1155/2011/179170
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