Targeting FCRLA to induce necrosis in lung adenocarcinoma: a novel strategy for prognosis and therapy via MPT-Driven pathways

Targeting FCRLA to induce necrosis in lung adenocarcinoma: a novel strategy for prognosis and therapy via MPT-Driven pathways

IntroductionThe induction of mitochondrial permeability transition-driven necrosis (MPTDN) is therapeutically relevant in various cancers. However, few studies have explored the role of MPTDN-related genes (MPTDNRGs) in lung adenocarcinoma (LUAD). Therefore, this study investigated the regulatory me...

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Bibliographic Details
Main Authors: Xiaoli Sun, Bowen Cai, Shusen Zhang, Xiaowei Cao, Zhen Wang, Zhigang Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
lung adenocarcinoma
mitochondrial permeability transition driven necrosis
FCRLA
risk model
new strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596179/full
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