Hidden pathway: the role of extracellular matrix in type 2 diabetes mellitus–related sarcopenia

Hidden pathway: the role of extracellular matrix in type 2 diabetes mellitus–related sarcopenia

Type 2 diabetes mellitus–related sarcopenia (T2DMRS) is a common complication in elderly and advanced diabetes patients that affects long-term prognosis and quality of life. Skeletal muscle is the main unit of glucose metabolism, and it is surrounded by extracellular matrix (ECM), which is a microen...

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Bibliographic Details
Main Authors: Yiping Sun, Zepeng Zhang, Yufeng Wang, Xingquan Wu, Yahui Sun, Huijuan Lou, Jing Xu, Junjie Yao, Deyu Cong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Endocrinology
Subjects:
extracellular matrix
type 2 diabetes
sarcopenia
collagen
integrins
skeletal muscle regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1560396/full
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