Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota

Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota

Background and purposeIschemic stroke (IS) is the most common type of stroke, known for its high rates of morbidity, disability, mortality, and recurrence. Polygoni Multiflori Radix Praeparata (PM), a traditional Chinese medicinal tonic, is frequently used for treating IS. Its polysaccharides (PMP)...

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Bibliographic Details
Main Authors: Lingyu Ruan, Zhennan Wang, Mengyun Zheng, Qi Zheng, Qing Qing, Hongyan Lin, Yuheng Tao, Liqun Wang, Junsong Wang, Wenhao Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
polygoni multiflori radix praeparata
polysaccharides
acute ischemic stroke
gut microbiota
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1580055/full
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