Effects of different kinds of dialysis on calcium-phosphorus metabolism and inflammatory factors in patients with end-stage renal disease
Objective To investigate the effects of different kinds of dialysis on calcium-phosphorus metabolism and inflammatory factors in patients with end-stage renal disease( ESRD). Methods250 ESRD patients treated in our hospital from January 2015 to December 2015 were divided into two groups given differ...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2017-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57916906&Fpath=home&index=0 |
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| Summary: | Objective To investigate the effects of different kinds of dialysis on calcium-phosphorus metabolism and inflammatory factors in patients with end-stage renal disease( ESRD). Methods250 ESRD patients treated in our hospital from January 2015 to December 2015 were divided into two groups given different dialysis procedures: 115 cases given peritoneal dialysis( PD),and the rest 135 cases hemodialysis( HD). All the patients were given a 6-month follow-up investigation. The inflammatory factors( CRP,IL-6,TNF-α) levels,calcium-phosphorus metabolism levels( Ca,P),biochemical index levels [total cholesterol( TC),triglyceride( TG),total protein( TP),hemoglobin( Hb),albumin( Alb),serum creatinine( SCr),and blood urea nitrogen( BUN) ],living quality and incidence of complications between two groups after treatment were compared. Results The C-reactive protein level in PD group was lower than that in HD group( P < 0. 05). There was no significant difference in IL-6,TNF-α,Ca and P levels between two groups( P > 0. 05). There was no significant difference in TC,TG,Hb,SCr and BUN between two groups( P > 0. 05). The TP and Alb in PD group were significantly lower than those in HD group( P < 0. 05). There was no significant difference in living quality between two groups( P > 0. 05). The incidence of infection and hypoproteinemia in PD group was significantly higher than that in HD group( P < 0. 05). The incidence of hypertension,arrhythmia and congestive heart failure in PD group was significantly lower than that in HD group( P < 0. 05). Conclusions ESRD patients with PD or HD have inflammatory response and patients with HD have more severe response. The effects of two kinds of dialysis on calcium-phosphorus metabolism have no significant difference. The suitable dialysis procedure should be selected in terms of patients’ clinical specific conditions. |
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| ISSN: | 1671-2390 |