Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols
Molecularly imprinted polymers (MIPs) are an effective method for separating enantiomeric compounds. The main objective of this research is to synthesize D-arabinitol MIPs, which can selectively separate D-arabinitol and its potential application to differentiate it from its enantio...
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University of Baghdad, College of Science for Women
2021-12-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5189 |
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| author | Yuni Retnaningtyas Ganden Supriyanto Roedi Irawan Siswandono Siswodihardjo |
| author_facet | Yuni Retnaningtyas Ganden Supriyanto Roedi Irawan Siswandono Siswodihardjo |
| author_sort | Yuni Retnaningtyas |
| collection | DOAJ |
| description | Molecularly imprinted polymers (MIPs) are an effective method for separating enantiomeric compounds. The main objective of this research is to synthesize D-arabinitol MIPs, which can selectively separate D-arabinitol and its potential application to differentiate it from its enantiomer compound through a non-covalent approach. A macroporous polymer was synthesized using D-arabinitol as a template, acrylamide as a functional monomer, ethylene glycol dimethacrylate (EGDMA) being a cross-linker, dimethylsulfoxide (DMSO) being a porogen, as well as benzoyl peroxide being an initiator. After polymer synthesis, D-arabinitol was removed by a mixture of methanol and acetic acid (4:1, v/v). Fourier-Transform Infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) distinguished the MIPs and NIPs. A selectivity test of MIPs against its enantiomers (L-arabinitol, xylitol, adonitol, and glucose) was carried out using the batch rebinding method. The binding site was quantitatively determined using the Langmuir equation. The results of the selectivity test showed that the MIPs produced was quite selective toward its enantiomer and could potentially be used to separate D-arabinitol from its enantiomer. |
| format | Article |
| id | doaj-art-41e07fb244b54a1cb011a8efe7c04e4e |
| institution | DOAJ |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | University of Baghdad, College of Science for Women |
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| series | مجلة بغداد للعلوم |
| spelling | doaj-art-41e07fb244b54a1cb011a8efe7c04e4e2025-08-20T03:14:49ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862021-12-01184(Suppl.)10.21123/bsj.2021.18.4(Suppl.).1536Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar AlcoholsYuni Retnaningtyas0Ganden Supriyanto1Roedi Irawan2Siswandono Siswodihardjo3Faculty of Pharmacy University of Jember, Jember, Indonesia.Department Chemistry Faculty of Science and Technology, University of Airlangga, Surabaya, Indonesia.Department paediatrics Faculty of Medicine University of Airlangga, Surabaya, Indonesia.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Airlangga, Surabaya, Indonesia.Molecularly imprinted polymers (MIPs) are an effective method for separating enantiomeric compounds. The main objective of this research is to synthesize D-arabinitol MIPs, which can selectively separate D-arabinitol and its potential application to differentiate it from its enantiomer compound through a non-covalent approach. A macroporous polymer was synthesized using D-arabinitol as a template, acrylamide as a functional monomer, ethylene glycol dimethacrylate (EGDMA) being a cross-linker, dimethylsulfoxide (DMSO) being a porogen, as well as benzoyl peroxide being an initiator. After polymer synthesis, D-arabinitol was removed by a mixture of methanol and acetic acid (4:1, v/v). Fourier-Transform Infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) distinguished the MIPs and NIPs. A selectivity test of MIPs against its enantiomers (L-arabinitol, xylitol, adonitol, and glucose) was carried out using the batch rebinding method. The binding site was quantitatively determined using the Langmuir equation. The results of the selectivity test showed that the MIPs produced was quite selective toward its enantiomer and could potentially be used to separate D-arabinitol from its enantiomer.https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5189D-arabinitol, Enantiomer, MIPs, Non-covalent, Selective material |
| spellingShingle | Yuni Retnaningtyas Ganden Supriyanto Roedi Irawan Siswandono Siswodihardjo Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols مجلة بغداد للعلوم D-arabinitol, Enantiomer, MIPs, Non-covalent, Selective material |
| title | Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols |
| title_full | Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols |
| title_fullStr | Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols |
| title_full_unstemmed | Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols |
| title_short | Noncovalently D-arabinitol Molecularly Imprinted Polymers (MIPs) to Identify Different Sugar Alcohols |
| title_sort | noncovalently d arabinitol molecularly imprinted polymers mips to identify different sugar alcohols |
| topic | D-arabinitol, Enantiomer, MIPs, Non-covalent, Selective material |
| url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5189 |
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