Optimizing the use of in vitro transcribed SGK1-mRNA as a therapeutic tool to treat female infertility
Abstract Objectives Gene therapy has emerged as an encouraging therapeutic approach for several diseases. The use of plasmid DNA (pDNA) or viral vectors encoding proteins have yielded low efficacy in recent trials. Synthetic messenger RNA (mRNA), also known as in vitro transcribed mRNA (IVT-mRNA), i...
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| Main Authors: | Itishri Sahu, Fabienne Engelmann, Brian Weidensee, Harivignesh Ganesan, Sara Y. Brucker, Yogesh Singh, Madhuri S. Salker |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13104-025-07346-5 |
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