Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs
The chloroplast FtsZ ring (Z ring) is assembled by two distinct FtsZ proteins, FtsZ2 and FtsZ1 (referred to as FtsZA and FtsZB in red algae). FtsZ2 confers stability to the Z ring, while FtsZ1 enhances its dynamics. Enhanced Z-ring dynamics is essential for Z-ring remodeling, which drives chloroplas...
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| Format: | Article |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2025.1622675/full |
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| author | Lingyan Cao Lingyan Cao Lingyan Cao Katie J. Porter Wenbin Du Emily J. Tallerday Moyang Liu Wanqi Liang Katherine W. Osteryoung Cheng Chen Cheng Chen Cheng Chen |
| author_facet | Lingyan Cao Lingyan Cao Lingyan Cao Katie J. Porter Wenbin Du Emily J. Tallerday Moyang Liu Wanqi Liang Katherine W. Osteryoung Cheng Chen Cheng Chen Cheng Chen |
| author_sort | Lingyan Cao |
| collection | DOAJ |
| description | The chloroplast FtsZ ring (Z ring) is assembled by two distinct FtsZ proteins, FtsZ2 and FtsZ1 (referred to as FtsZA and FtsZB in red algae). FtsZ2 confers stability to the Z ring, while FtsZ1 enhances its dynamics. Enhanced Z-ring dynamics is essential for Z-ring remodeling, which drives chloroplast constriction and division. However, the mechanisms underlying the distinct dynamic properties of the two FtsZs remain unclear. Here, we report that the conserved core regions are primarily responsible for the distinct dynamic properties observed in both plant and red algal FtsZs. We demonstrate that the conserved core region of FtsZ1 enhances the dynamics of FtsZ2 within coassembled filaments. Likewise, we show that the conserved core region of red algal FtsZB promotes the dynamics of coassembled FtsZA rings. Our findings provide evidence that the evolution of a second FtsZ protein represents a general mechanism to enhance the dynamics of the chloroplast Z ring. |
| format | Article |
| id | doaj-art-41d2c179e0fd4f358599dfdd1702cdfa |
| institution | Kabale University |
| issn | 1664-462X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj-art-41d2c179e0fd4f358599dfdd1702cdfa2025-08-20T03:56:09ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-07-011610.3389/fpls.2025.16226751622675Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZsLingyan Cao0Lingyan Cao1Lingyan Cao2Katie J. Porter3Wenbin Du4Emily J. Tallerday5Moyang Liu6Wanqi Liang7Katherine W. Osteryoung8Cheng Chen9Cheng Chen10Cheng Chen11Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Plant Biology, Michigan State University, East Lansing, MI, United StatesDepartment of Plant Sciences, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Plant Biology, Michigan State University, East Lansing, MI, United StatesDepartment of Plant Sciences, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Plant Biology, Michigan State University, East Lansing, MI, United StatesDepartment of Plant Sciences, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, ChinaJoint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Plant Biology, Michigan State University, East Lansing, MI, United StatesDepartment of Plant Sciences, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, ChinaShanghai Collaborative Innovation Center of Agri-Seeds, Shanghai Jiao Tong University, Shanghai, ChinaJoint Center for Single Cell Biology, Shanghai Jiao Tong University, Shanghai, ChinaThe chloroplast FtsZ ring (Z ring) is assembled by two distinct FtsZ proteins, FtsZ2 and FtsZ1 (referred to as FtsZA and FtsZB in red algae). FtsZ2 confers stability to the Z ring, while FtsZ1 enhances its dynamics. Enhanced Z-ring dynamics is essential for Z-ring remodeling, which drives chloroplast constriction and division. However, the mechanisms underlying the distinct dynamic properties of the two FtsZs remain unclear. Here, we report that the conserved core regions are primarily responsible for the distinct dynamic properties observed in both plant and red algal FtsZs. We demonstrate that the conserved core region of FtsZ1 enhances the dynamics of FtsZ2 within coassembled filaments. Likewise, we show that the conserved core region of red algal FtsZB promotes the dynamics of coassembled FtsZA rings. Our findings provide evidence that the evolution of a second FtsZ protein represents a general mechanism to enhance the dynamics of the chloroplast Z ring.https://www.frontiersin.org/articles/10.3389/fpls.2025.1622675/fullchloroplastFtsZ-ringdynamicsdivisionevolution |
| spellingShingle | Lingyan Cao Lingyan Cao Lingyan Cao Katie J. Porter Wenbin Du Emily J. Tallerday Moyang Liu Wanqi Liang Katherine W. Osteryoung Cheng Chen Cheng Chen Cheng Chen Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs Frontiers in Plant Science chloroplast FtsZ-ring dynamics division evolution |
| title | Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs |
| title_full | Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs |
| title_fullStr | Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs |
| title_full_unstemmed | Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs |
| title_short | Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs |
| title_sort | chloroplast z ring dynamics is governed by conserved core regions of evolutionarily divergent ftszs |
| topic | chloroplast FtsZ-ring dynamics division evolution |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2025.1622675/full |
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