NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing

NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing

Summary: Conventional treatments for advanced endometriosis often have limited efficacy due to chemotherapy resistance, recurrence, and metastasis. This study analyzed clinical specimens to investigate the role of NXF1 in endometrial cancer (ECa) progression. Mouse models and molecular biology assay...

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Bibliographic Details
Main Authors: Nan Meng, Lingjun Li, Xueqin Yang, Hui Tang, Jizhong Wang, Songbai Zhang, Zongbao Xia, Jia Yao, Qi Zhang, Changrong Hu, Chunjie Su, Rui Duan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Cancer
Cell biology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013744
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