CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks

CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks

Abstract DNA-protein interactions have traditionally been profiled via chromatin immunoprecipitation followed by next-generation sequencing (ChIP-seq). Cleavage Under Targets & Tagmentation (CUT&Tag) is a rapidly expanding technique that enables the profiling of such interactions in situ at...

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Bibliographic Details
Main Authors: Leyla Abbasova, Paulina Urbanaviciute, Di Hu, Joy N. Ismail, Brian M. Schilder, Alexi Nott, Nathan G. Skene, Sarah J. Marzi
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58137-2
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