Early-detection of pre-eclampsia: Concept and design of a portable prototype

Pre-eclampsia is one of the most common causes of maternal and perinatal death worldwide. It is a hypertensive pregnancy disease with reduced perfusion of numerous organs. The main symptoms of the disease include elevated blood pressure, proteinuria and the associated subcutaneous fluid retention in...

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Main Authors: Janzen Swantje, Wagner Jessica, Pott Peter P.
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Current Directions in Biomedical Engineering
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Online Access:https://doi.org/10.1515/cdbme-2024-2083
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author Janzen Swantje
Wagner Jessica
Pott Peter P.
author_facet Janzen Swantje
Wagner Jessica
Pott Peter P.
author_sort Janzen Swantje
collection DOAJ
description Pre-eclampsia is one of the most common causes of maternal and perinatal death worldwide. It is a hypertensive pregnancy disease with reduced perfusion of numerous organs. The main symptoms of the disease include elevated blood pressure, proteinuria and the associated subcutaneous fluid retention in the fingers, hands and face of the pregnant woman. In this paper a concept of a portable prototype for early-detection of preeclampsia is presented. The assembled sensor systems enable portable monitoring of the main symptoms to detect changes at an early stage. The sensor system for determining blood pressure is based on photoplethysmography. The sensor system for detecting subcutaneous fluid retention uses the absorption bands of the fluid when illuminated with near-infrared light. For the validation experiments, finger models made of silicone with different fluid retention levels were produced. The results show a correlation between the measured transmitted light intensity and the fluid retention. The results represent a possibility for the portable measurement of important vital parameters in connection with preeclampsia.
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issn 2364-5504
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series Current Directions in Biomedical Engineering
spelling doaj-art-41bb7fd66b854f7a913ea8dc70c5392f2025-08-20T02:51:59ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110434034310.1515/cdbme-2024-2083Early-detection of pre-eclampsia: Concept and design of a portable prototypeJanzen Swantje0Wagner Jessica1Pott Peter P.2Institute of Medical Device Technology, University of Stuttgart, Pfaffenwaldring 9, 70569Stuttgart, GermanyInstitute of Medical Device Technology, University of Stuttgart,Stuttgart, GermanyInstitute of Medical Device Technology, University of Stuttgart,Stuttgart, GermanyPre-eclampsia is one of the most common causes of maternal and perinatal death worldwide. It is a hypertensive pregnancy disease with reduced perfusion of numerous organs. The main symptoms of the disease include elevated blood pressure, proteinuria and the associated subcutaneous fluid retention in the fingers, hands and face of the pregnant woman. In this paper a concept of a portable prototype for early-detection of preeclampsia is presented. The assembled sensor systems enable portable monitoring of the main symptoms to detect changes at an early stage. The sensor system for determining blood pressure is based on photoplethysmography. The sensor system for detecting subcutaneous fluid retention uses the absorption bands of the fluid when illuminated with near-infrared light. For the validation experiments, finger models made of silicone with different fluid retention levels were produced. The results show a correlation between the measured transmitted light intensity and the fluid retention. The results represent a possibility for the portable measurement of important vital parameters in connection with preeclampsia.https://doi.org/10.1515/cdbme-2024-2083pre-eclampsiaearly-detectionphotoplethysmographysubcutaneous fluid retention
spellingShingle Janzen Swantje
Wagner Jessica
Pott Peter P.
Early-detection of pre-eclampsia: Concept and design of a portable prototype
Current Directions in Biomedical Engineering
pre-eclampsia
early-detection
photoplethysmography
subcutaneous fluid retention
title Early-detection of pre-eclampsia: Concept and design of a portable prototype
title_full Early-detection of pre-eclampsia: Concept and design of a portable prototype
title_fullStr Early-detection of pre-eclampsia: Concept and design of a portable prototype
title_full_unstemmed Early-detection of pre-eclampsia: Concept and design of a portable prototype
title_short Early-detection of pre-eclampsia: Concept and design of a portable prototype
title_sort early detection of pre eclampsia concept and design of a portable prototype
topic pre-eclampsia
early-detection
photoplethysmography
subcutaneous fluid retention
url https://doi.org/10.1515/cdbme-2024-2083
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