The role of nuclear receptors in metabolic homeostasis and disease: From molecular mechanisms to drug discovery

The role of nuclear receptors in metabolic homeostasis and disease: From molecular mechanisms to drug discovery

Nuclear receptors (NRs) are a superfamily of ligand-dependent transcription factors that serve as pivotal regulators of gene expression in response to hormonal, metabolic, and environmental cues. They exert transcriptional control through complex interactions with co-regulators, thereby influencing...

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Bibliographic Details
Main Authors: Fangfang He, Haomeng Wu, Feilong Zhao, Xinxin Liu, Qin Yang, Shiquan Zhou, Tianling Xu, Jing Xu, Shuai Wang, Denglang Zou
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Pharmacological Research
Subjects:
Nuclear receptor
Metabolism
Disease
Drug development
Pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825002816
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