The potential of using itaconate as treatment for inflammation-related heart diseases

Intracellular metabolites can cause critical changes in biological functions. Itaconate is perhaps the most fascinating substance in macrophages. Lipopolysaccharide can activate aconitate decarboxylase 1 and induces the generation of itaconate from the tricarboxylic acid cycle by decarboxylation of...

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Bibliographic Details
Main Authors: Hui-Chen Ku, Ta-Chung Shen, Ching-Feng Cheng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Tzu Chi Medical Journal
Subjects:
Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2022;volume=34;issue=2;spage=113;epage=118;aulast=Ku
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