Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients
Better and balanced information strategies supporting cardiovascular patients’ adherence are required. Cardiovascular drugs have outstanding morbidity and mortality benefits. This can be counteracted by patients’ perceptions of risks. Drug information should help the patient but not fuel unwarranted...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/6585271 |
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| author | Ines Wakob Ina Wintsche Annett Frisch Yvonne Remane Ulrich Laufs Thilo Bertsche Susanne Schiek |
| author_facet | Ines Wakob Ina Wintsche Annett Frisch Yvonne Remane Ulrich Laufs Thilo Bertsche Susanne Schiek |
| author_sort | Ines Wakob |
| collection | DOAJ |
| description | Better and balanced information strategies supporting cardiovascular patients’ adherence are required. Cardiovascular drugs have outstanding morbidity and mortality benefits. This can be counteracted by patients’ perceptions of risks. Drug information should help the patient but not fuel unwarranted fears. We performed a cross-sectional survey of patients admitted to a cardiology ward. We evaluated (i) the patients’ general benefit-risk estimation of their pharmacotherapy; (ii) views on benefits; (iii) views on risks; and (iv) information sources. Additionally, we assessed aspects of anxiety and depression with the Patient Health Questionnaire-4 (PHQ-4). (i) 67 patients (66%) rated expected drug benefits higher than potential risks. (ii) 72% of benefits motivated the patients to take their medication as prescribed. Patients more frequently mentioned surrogate markers as benefits than clinical benefits (p<0.001). (iii) 56% of risks mentioned were perceived as bothersome and 35% as concerning. Risks were more often perceived as bothersome and concerning by patients with higher PHQ-4 scores (p=0.016). (iv) Physicians were the most frequent information source of benefits (92% of patients) and risks (45%), and pharmacy staff for 27% and 14%, respectively. Laymen or media served as sources of information on benefits in 39%, for risks in 40%, and package leaflets in 26% and 36%. 42% of the patients would like to receive more information on benefits versus 27% on risks. Our results suggest that knowledge of benefits motivates patients to take their drugs as prescribed. There is already good information on surrogate markers for process control with active patient involvement. However, a lack of knowledge still exists in relation to clinical benefits. Regarding risks, it has been shown that patients with higher PHQ-4 scores are more likely to be bothered or concerned. Both emphases on clinical benefits and individualization depending on PHQ-4 scores may be valuable resources for patient counseling to support adherence. |
| format | Article |
| id | doaj-art-41b363acf43f4c34be67343cbae737d5 |
| institution | OA Journals |
| issn | 1742-1241 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Clinical Practice |
| spelling | doaj-art-41b363acf43f4c34be67343cbae737d52025-08-20T02:08:24ZengWileyInternational Journal of Clinical Practice1742-12412022-01-01202210.1155/2022/6585271Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular PatientsInes Wakob0Ina Wintsche1Annett Frisch2Yvonne Remane3Ulrich Laufs4Thilo Bertsche5Susanne Schiek6Clinical PharmacyClinical PharmacyDrug Safety CenterDrug Safety CenterKlinik und Poliklinik für KardiologieClinical PharmacyClinical PharmacyBetter and balanced information strategies supporting cardiovascular patients’ adherence are required. Cardiovascular drugs have outstanding morbidity and mortality benefits. This can be counteracted by patients’ perceptions of risks. Drug information should help the patient but not fuel unwarranted fears. We performed a cross-sectional survey of patients admitted to a cardiology ward. We evaluated (i) the patients’ general benefit-risk estimation of their pharmacotherapy; (ii) views on benefits; (iii) views on risks; and (iv) information sources. Additionally, we assessed aspects of anxiety and depression with the Patient Health Questionnaire-4 (PHQ-4). (i) 67 patients (66%) rated expected drug benefits higher than potential risks. (ii) 72% of benefits motivated the patients to take their medication as prescribed. Patients more frequently mentioned surrogate markers as benefits than clinical benefits (p<0.001). (iii) 56% of risks mentioned were perceived as bothersome and 35% as concerning. Risks were more often perceived as bothersome and concerning by patients with higher PHQ-4 scores (p=0.016). (iv) Physicians were the most frequent information source of benefits (92% of patients) and risks (45%), and pharmacy staff for 27% and 14%, respectively. Laymen or media served as sources of information on benefits in 39%, for risks in 40%, and package leaflets in 26% and 36%. 42% of the patients would like to receive more information on benefits versus 27% on risks. Our results suggest that knowledge of benefits motivates patients to take their drugs as prescribed. There is already good information on surrogate markers for process control with active patient involvement. However, a lack of knowledge still exists in relation to clinical benefits. Regarding risks, it has been shown that patients with higher PHQ-4 scores are more likely to be bothered or concerned. Both emphases on clinical benefits and individualization depending on PHQ-4 scores may be valuable resources for patient counseling to support adherence.http://dx.doi.org/10.1155/2022/6585271 |
| spellingShingle | Ines Wakob Ina Wintsche Annett Frisch Yvonne Remane Ulrich Laufs Thilo Bertsche Susanne Schiek Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients International Journal of Clinical Practice |
| title | Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients |
| title_full | Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients |
| title_fullStr | Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients |
| title_full_unstemmed | Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients |
| title_short | Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients |
| title_sort | assessment of patients views on drug benefits and risks an interview study with cardiovascular patients |
| url | http://dx.doi.org/10.1155/2022/6585271 |
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