Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects
Our goal was to develop and experimentally validate a polarization-interference method for phase scanning of laser speckle fields generated by diffuse layers of birefringent biological tissues. This method isolates and uses new diagnostic parameters related to the “phase waves of local depolarizatio...
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| Language: | English |
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World Scientific Publishing
2025-09-01
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| Series: | Journal of Innovative Optical Health Sciences |
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| Online Access: | https://www.worldscientific.com/doi/10.1142/S1793545825500099 |
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| author | Yurii Ushenko Alexander Ushenko Alexander Dubolazov Mykhaylo Gorsky Irina Soltys Olexandra Litvinenko Victor Bachinsky Ivan Mikirin Olexander Salega Ivan Garasim Jun Zheng Lin Bin |
| author_facet | Yurii Ushenko Alexander Ushenko Alexander Dubolazov Mykhaylo Gorsky Irina Soltys Olexandra Litvinenko Victor Bachinsky Ivan Mikirin Olexander Salega Ivan Garasim Jun Zheng Lin Bin |
| author_sort | Yurii Ushenko |
| collection | DOAJ |
| description | Our goal was to develop and experimentally validate a polarization-interference method for phase scanning of laser speckle fields generated by diffuse layers of birefringent biological tissues. This method isolates and uses new diagnostic parameters related to the “phase waves of local depolarization”. We combined polarization-interference registration with phase scanning of complex amplitude distributions in diffuse laser speckle fields to detect phase waves of local depolarization in birefringent fibrillar networks of biological tissue and measure their modulation depth. This approach led to the discovery of new criteria for differentiating various necrotic changes in diffuse histological samples of myocardial tissue from deceased individuals with “ischemic heart disease (IHD) — acute coronary insufficiency (ACI)”, even in the presence of a high level of depolarized background. To evaluate the degree of necrotic changes in the optical anisotropy of diffuse myocardial layers, a new quantitative parameter — modulation depth of local depolarization wave fluctuations — has been proposed. Using this approach, for the first time, differentiation of diffuse myocardial samples from deceased individuals with IHD and ACI was achieved with a very good 90.45% and outstanding accuracy of 95.2%. |
| format | Article |
| id | doaj-art-41a68759eab14d09987f331b31c897ff |
| institution | DOAJ |
| issn | 1793-5458 1793-7205 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Innovative Optical Health Sciences |
| spelling | doaj-art-41a68759eab14d09987f331b31c897ff2025-08-20T02:46:57ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052025-09-01180510.1142/S1793545825500099Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspectsYurii Ushenko0Alexander Ushenko1Alexander Dubolazov2Mykhaylo Gorsky3Irina Soltys4Olexandra Litvinenko5Victor Bachinsky6Ivan Mikirin7Olexander Salega8Ivan Garasim9Jun Zheng10Lin Bin11Department of Physics, Shaoxing University, Shaoxing, Zhejiang 312000, P. R. ChinaTaizhou Institute of Zhejiang University, Taizhou 310027, P. R. ChinaOptics and Publishing Department, Chernivtsi National University, Chernivtsi, UkraineComputer Science Department, Chernivtsi National University, Chernivtsi, UkraineOptics and Publishing Department, Chernivtsi National University, Chernivtsi, UkraineForensic Medicine and Medical Law Department, Bukovinian State Medical University, Chernivtsi, UkraineForensic Medicine and Medical Law Department, Bukovinian State Medical University, Chernivtsi, UkraineOptics and Publishing Department, Chernivtsi National University, Chernivtsi, UkraineOptics and Publishing Department, Chernivtsi National University, Chernivtsi, UkraineOptics and Publishing Department, Chernivtsi National University, Chernivtsi, UkraineComputer Science Department, Chernivtsi National University, Chernivtsi, UkraineZhejiang University, Hangzhou, P. R. ChinaOur goal was to develop and experimentally validate a polarization-interference method for phase scanning of laser speckle fields generated by diffuse layers of birefringent biological tissues. This method isolates and uses new diagnostic parameters related to the “phase waves of local depolarization”. We combined polarization-interference registration with phase scanning of complex amplitude distributions in diffuse laser speckle fields to detect phase waves of local depolarization in birefringent fibrillar networks of biological tissue and measure their modulation depth. This approach led to the discovery of new criteria for differentiating various necrotic changes in diffuse histological samples of myocardial tissue from deceased individuals with “ischemic heart disease (IHD) — acute coronary insufficiency (ACI)”, even in the presence of a high level of depolarized background. To evaluate the degree of necrotic changes in the optical anisotropy of diffuse myocardial layers, a new quantitative parameter — modulation depth of local depolarization wave fluctuations — has been proposed. Using this approach, for the first time, differentiation of diffuse myocardial samples from deceased individuals with IHD and ACI was achieved with a very good 90.45% and outstanding accuracy of 95.2%.https://www.worldscientific.com/doi/10.1142/S1793545825500099Polarizationdepolarizationinterferencephase scanningoptical anisotropybirefringence |
| spellingShingle | Yurii Ushenko Alexander Ushenko Alexander Dubolazov Mykhaylo Gorsky Irina Soltys Olexandra Litvinenko Victor Bachinsky Ivan Mikirin Olexander Salega Ivan Garasim Jun Zheng Lin Bin Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects Journal of Innovative Optical Health Sciences Polarization depolarization interference phase scanning optical anisotropy birefringence |
| title | Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects |
| title_full | Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects |
| title_fullStr | Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects |
| title_full_unstemmed | Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects |
| title_short | Phase waves of local depolarization in biological tissues object speckle fields. Fundamental and applied aspects |
| title_sort | phase waves of local depolarization in biological tissues object speckle fields fundamental and applied aspects |
| topic | Polarization depolarization interference phase scanning optical anisotropy birefringence |
| url | https://www.worldscientific.com/doi/10.1142/S1793545825500099 |
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