A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features
Introduction: Colonic pseudolipomatosis is a rare benign lesion with distinct endoscopic and histological features. The etiology and pathogenesis of colonic pseudolipomatosis have not been fully clarified and are still controversial to some extent. It is particularly noteworthy that this...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2025-02-01
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| Series: | Case Reports in Gastroenterology |
| Online Access: | https://karger.com/article/doi/10.1159/000543951 |
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| author | Qi Zhao Hai-Tao Yu Qun-Ying Wang Wei Zhang Wen-Zhu Dong |
| author_facet | Qi Zhao Hai-Tao Yu Qun-Ying Wang Wei Zhang Wen-Zhu Dong |
| author_sort | Qi Zhao |
| collection | DOAJ |
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Introduction: Colonic pseudolipomatosis is a rare benign lesion with distinct endoscopic and histological features. The etiology and pathogenesis of colonic pseudolipomatosis have not been fully clarified and are still controversial to some extent. It is particularly noteworthy that this lesion must be differentiated from real pathological entities to avoid further unnecessary auxiliary examinations and overtreatments. Case Presentation: We report a case of a 61-year-old woman who underwent regular postoperative follow-ups of rectal cancer. The colonoscopy showed multiple slightly elevated whitish plaques with irregular shapes in almost all of the colon. The plaques were biopsied to further define the focal nature. Further histopathological examination revealed numerous scattered or clustered adipocyte-like vacuoles in lamina propria. Immunohistochemistry results were negative for anti-CD34 and anti-protein S-100, supporting the diagnosis of pseudolipomatosis. Conclusion: Colonic pseudolipomatosis is a rare and benign self-limiting condition that should not be mistaken for a pathological entity, especially active inflammation or malignant tumor. Endoscopic lesions commonly regress spontaneously without complications and appropriate management is necessary because it requires no further investigations or treatments. |
| format | Article |
| id | doaj-art-418ace344b584aed83008e4a911ffe91 |
| institution | Kabale University |
| issn | 1662-0631 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj-art-418ace344b584aed83008e4a911ffe912025-08-20T03:49:41ZengKarger PublishersCase Reports in Gastroenterology1662-06312025-02-0119112713310.1159/000543951A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological FeaturesQi ZhaoHai-Tao YuQun-Ying WangWei ZhangWen-Zhu Dong Introduction: Colonic pseudolipomatosis is a rare benign lesion with distinct endoscopic and histological features. The etiology and pathogenesis of colonic pseudolipomatosis have not been fully clarified and are still controversial to some extent. It is particularly noteworthy that this lesion must be differentiated from real pathological entities to avoid further unnecessary auxiliary examinations and overtreatments. Case Presentation: We report a case of a 61-year-old woman who underwent regular postoperative follow-ups of rectal cancer. The colonoscopy showed multiple slightly elevated whitish plaques with irregular shapes in almost all of the colon. The plaques were biopsied to further define the focal nature. Further histopathological examination revealed numerous scattered or clustered adipocyte-like vacuoles in lamina propria. Immunohistochemistry results were negative for anti-CD34 and anti-protein S-100, supporting the diagnosis of pseudolipomatosis. Conclusion: Colonic pseudolipomatosis is a rare and benign self-limiting condition that should not be mistaken for a pathological entity, especially active inflammation or malignant tumor. Endoscopic lesions commonly regress spontaneously without complications and appropriate management is necessary because it requires no further investigations or treatments.https://karger.com/article/doi/10.1159/000543951 |
| spellingShingle | Qi Zhao Hai-Tao Yu Qun-Ying Wang Wei Zhang Wen-Zhu Dong A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features Case Reports in Gastroenterology |
| title | A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features |
| title_full | A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features |
| title_fullStr | A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features |
| title_full_unstemmed | A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features |
| title_short | A Rare Case Report of Colonic Pseudolipomatosis with Distinct Endoscopic and Histological Features |
| title_sort | rare case report of colonic pseudolipomatosis with distinct endoscopic and histological features |
| url | https://karger.com/article/doi/10.1159/000543951 |
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