Single-cell transcriptomics analysis reveals a disrupted NK-T cell interaction network in liver metastatic cancer

Abstract Natural killer (NK) cells and T cells play crucial roles in liver metastatic cancer, particularly through their cytotoxic effects on tumor cells. Although existing evidence suggests a functional network of mutual regulation between NK and T cells, the nature of their interaction and its rol...

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Bibliographic Details
Main Authors: Xiaoshuang Wang, Zhongen Wu, Yan Zhou, Dehua Yang, Qingtong Zhou, Di Zhu, Ming-Wei Wang, Lu Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-06241-0
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