Salivary glands regenerate after radiation injury through SOX2‐mediated secretory cell replacement
Abstract Salivary gland acinar cells are routinely destroyed during radiation treatment for head and neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential regenerative strategy for replacing injured tissue is the reactivation of endogenous stem cells by targeted th...
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| Main Authors: | Elaine Emmerson, Alison J May, Lionel Berthoin, Noel Cruz‐Pacheco, Sara Nathan, Aaron J Mattingly, Jolie L Chang, William R Ryan, Aaron D Tward, Sarah M Knox |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-01-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201708051 |
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