Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes

Systemically administered glucocorticoids constitute an essential part of the immunosuppressive regimen for transplant recipients, yet their known risks of causing hyperglycemia or posttransplant diabetes require close monitoring and minimisation of use, when possible, to prevent detrimental effects...

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Main Authors: Simon Bøtker, Henrik Birn, Lara Aygen Øzbay
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2023/3648178
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author Simon Bøtker
Henrik Birn
Lara Aygen Øzbay
author_facet Simon Bøtker
Henrik Birn
Lara Aygen Øzbay
author_sort Simon Bøtker
collection DOAJ
description Systemically administered glucocorticoids constitute an essential part of the immunosuppressive regimen for transplant recipients, yet their known risks of causing hyperglycemia or posttransplant diabetes require close monitoring and minimisation of use, when possible, to prevent detrimental effects on patient morbidity and graft survival. Topical glucocorticoids, on the other hand, are rarely considered to affect glucose metabolism and therefore seldomly monitored, despite their wide and in some cases, long-term use. We report a case of a renal transplant recipient presenting with acute hyperosmolar hyperglycemia after treatment with topical glucocorticoids and present a mini review of the literature.
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institution Kabale University
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spelling doaj-art-4173e337c2ce43d9a11b777ad089145d2025-02-03T06:08:39ZengWileyCase Reports in Endocrinology2090-651X2023-01-01202310.1155/2023/3648178Topical Glucocorticoid Use and the Risk of Posttransplant DiabetesSimon Bøtker0Henrik Birn1Lara Aygen Øzbay2Department of NephrologyDepartment of NephrologyDepartment of NephrologySystemically administered glucocorticoids constitute an essential part of the immunosuppressive regimen for transplant recipients, yet their known risks of causing hyperglycemia or posttransplant diabetes require close monitoring and minimisation of use, when possible, to prevent detrimental effects on patient morbidity and graft survival. Topical glucocorticoids, on the other hand, are rarely considered to affect glucose metabolism and therefore seldomly monitored, despite their wide and in some cases, long-term use. We report a case of a renal transplant recipient presenting with acute hyperosmolar hyperglycemia after treatment with topical glucocorticoids and present a mini review of the literature.http://dx.doi.org/10.1155/2023/3648178
spellingShingle Simon Bøtker
Henrik Birn
Lara Aygen Øzbay
Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
Case Reports in Endocrinology
title Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
title_full Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
title_fullStr Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
title_full_unstemmed Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
title_short Topical Glucocorticoid Use and the Risk of Posttransplant Diabetes
title_sort topical glucocorticoid use and the risk of posttransplant diabetes
url http://dx.doi.org/10.1155/2023/3648178
work_keys_str_mv AT simonbøtker topicalglucocorticoiduseandtheriskofposttransplantdiabetes
AT henrikbirn topicalglucocorticoiduseandtheriskofposttransplantdiabetes
AT laraaygenøzbay topicalglucocorticoiduseandtheriskofposttransplantdiabetes