Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)

Monitoring infectious diseases is essential for safeguarding equine health and ensuring the sustainability of the horse industry. In 2019, the Royal Veterinary Association of the Netherlands (KNMvD) and Royal GD (GD Animal Health) launched SEIN (Surveillance of Equine Infectious diseases in the Neth...

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Main Authors: Kees van Maanen, Linda van den Wollenberg, Tara de Haan, Thibault Frippiat
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Veterinary Sciences
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Online Access:https://www.mdpi.com/2306-7381/12/6/567
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author Kees van Maanen
Linda van den Wollenberg
Tara de Haan
Thibault Frippiat
author_facet Kees van Maanen
Linda van den Wollenberg
Tara de Haan
Thibault Frippiat
author_sort Kees van Maanen
collection DOAJ
description Monitoring infectious diseases is essential for safeguarding equine health and ensuring the sustainability of the horse industry. In 2019, the Royal Veterinary Association of the Netherlands (KNMvD) and Royal GD (GD Animal Health) launched SEIN (Surveillance of Equine Infectious diseases in the Netherlands), a voluntary surveillance system for laboratory-confirmed outbreaks of equid alphaherpesvirus 1 (EHV-1), equid alphaherpesvirus 4 (EHV-4), equine influenza virus (EIV), and <i>Streptococcus equi</i> subsp. <i>equi</i>. This retrospective study analyzed 364 confirmed outbreaks reported through SEIN between June 2019 and April 2023. <i>S. equi</i> was the most commonly reported pathogen overall (64%). Among outbreaks involving respiratory disease, <i>S. equi</i> accounted for 74% of cases, followed by EHV-4 (16%), EIV (6%), and EHV-1 (4%). The geographical distribution of outbreaks covered 80 of the 90 postal code regions (89%), and approximately half of all participating practices generated at least 1 alert. Vaccination data revealed low coverage against EHV-1/4, EIV, and <i>S. equi</i> among both affected horses and premises. Clinical signs overlapped between pathogens, but some were more pathogen-specific, e.g., coughing in EIV, and abscessation in <i>S. equi</i>. The SEIN system provided spatiotemporal information on confirmed outbreaks. These results underscore the importance of quick diagnostics and structured surveillance systems in guiding prevention strategies.
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spelling doaj-art-4170bb13519a4f30bdbfae23f0d45f8a2025-08-20T03:32:32ZengMDPI AGVeterinary Sciences2306-73812025-06-0112656710.3390/vetsci12060567Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)Kees van Maanen0Linda van den Wollenberg1Tara de Haan2Thibault Frippiat3Royal GD, 7418EZ Deventer, The NetherlandsRoyal GD, 7418EZ Deventer, The NetherlandsRoyal GD, 7418EZ Deventer, The NetherlandsSporthorse Medical Diagnostic Centre, 5384RC Heesch, The NetherlandsMonitoring infectious diseases is essential for safeguarding equine health and ensuring the sustainability of the horse industry. In 2019, the Royal Veterinary Association of the Netherlands (KNMvD) and Royal GD (GD Animal Health) launched SEIN (Surveillance of Equine Infectious diseases in the Netherlands), a voluntary surveillance system for laboratory-confirmed outbreaks of equid alphaherpesvirus 1 (EHV-1), equid alphaherpesvirus 4 (EHV-4), equine influenza virus (EIV), and <i>Streptococcus equi</i> subsp. <i>equi</i>. This retrospective study analyzed 364 confirmed outbreaks reported through SEIN between June 2019 and April 2023. <i>S. equi</i> was the most commonly reported pathogen overall (64%). Among outbreaks involving respiratory disease, <i>S. equi</i> accounted for 74% of cases, followed by EHV-4 (16%), EIV (6%), and EHV-1 (4%). The geographical distribution of outbreaks covered 80 of the 90 postal code regions (89%), and approximately half of all participating practices generated at least 1 alert. Vaccination data revealed low coverage against EHV-1/4, EIV, and <i>S. equi</i> among both affected horses and premises. Clinical signs overlapped between pathogens, but some were more pathogen-specific, e.g., coughing in EIV, and abscessation in <i>S. equi</i>. The SEIN system provided spatiotemporal information on confirmed outbreaks. These results underscore the importance of quick diagnostics and structured surveillance systems in guiding prevention strategies.https://www.mdpi.com/2306-7381/12/6/567equine influenzaequine herpesvirusstrangles<i>Streptococcus equi</i>epidemiologymicrobiology
spellingShingle Kees van Maanen
Linda van den Wollenberg
Tara de Haan
Thibault Frippiat
Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
Veterinary Sciences
equine influenza
equine herpesvirus
strangles
<i>Streptococcus equi</i>
epidemiology
microbiology
title Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
title_full Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
title_fullStr Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
title_full_unstemmed Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
title_short Epidemiology of Infectious Pathogens in Horses with Acute Respiratory Disease, Abortion, and Neurological Signs: Insights Gained from the Veterinary Surveillance System for Horses in The Netherlands (SEIN)
title_sort epidemiology of infectious pathogens in horses with acute respiratory disease abortion and neurological signs insights gained from the veterinary surveillance system for horses in the netherlands sein
topic equine influenza
equine herpesvirus
strangles
<i>Streptococcus equi</i>
epidemiology
microbiology
url https://www.mdpi.com/2306-7381/12/6/567
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