Mycological profile of dermatomycoses in Macedonian patients
Dermatomycoses are among the most common skin conditions that present a major public health problem. The aim of this study was to retrospectively analyse the mycological profile of dermatomycoses during a 6-year period (2017-2022). Specimens from 674 patients (384 nails 244 skin scrapings and 46 h...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association
2025-12-01
|
| Series: | Makedonsko Farmacevtski Bilten |
| Subjects: | |
| Online Access: | http://bulletin.mfd.org.mk/volumes/Volume%2071_2/71_2_005.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849316977969987584 |
|---|---|
| author | Gordana Mirchevska Emel Dauti Jahja Sanja Kostova-Ilieva Nadica Krsteva Aleksandra Kacarska Marija Kostovska-Micevska Elena Trajkovska-Dokic Zorica Zafirovik |
| author_facet | Gordana Mirchevska Emel Dauti Jahja Sanja Kostova-Ilieva Nadica Krsteva Aleksandra Kacarska Marija Kostovska-Micevska Elena Trajkovska-Dokic Zorica Zafirovik |
| author_sort | Gordana Mirchevska |
| collection | DOAJ |
| description | Dermatomycoses are among the most common skin conditions that present a major public health problem. The aim of this study was
to retrospectively analyse the mycological profile of dermatomycoses during a 6-year period (2017-2022). Specimens from 674 patients
(384 nails 244 skin scrapings and 46 hair specimens) with dermatomycoses were examined. The specimens were evaluated with
conventional mycological methods at the Institute of Microbiology and Parasitology, Skopje. Forty-seven percent of the samples were found to be culture positive. Samples from females were positive more frequently (192/317) than in males (125/317). The commonest age group was 11-20 years. The most prevalent etiological agents were non-dermatophyte molds56% (178/317), followed by yeasts in 30% (96/317), and dermatophytes in 13.6% (43/317). Almost 61% percent of the positive findings originated from nail specimens (192/317), 38% from skin scrapings (121/317), and 1.3% from hair specimens (4/317). Onychomycoses were caused by non-dermatophyte molds in 67% (128/192). Yeasts were identified in nail samples in 30% (57/192). Dermatophytes were agents of onychomycoses in 3.7% (7/192). Skin infections were caused by non-dermatophyte molds in 41.3% (50/121). Yeasts were identified in skin scrapings in 32% (39/121). Dermatophytes caused skin infections in 26.4% (32/121). Only 4 hair specimens were positive for dermatophytes.
Our study reflects an increasing role of non-dermatophyte fungi as a causative agent of dermatomycoses, replacing dermatophytes.
Clinicians’ awareness that molds can be contaminants of specimens, along with request for consecutive specimens can help in etiological
diagnosis of dermatomycoses, leading to successful treatment and prevention of disease recurrence.
|
| format | Article |
| id | doaj-art-416df0c1275e43b19496ebcdec3894d9 |
| institution | Kabale University |
| issn | 1409-8695 1857-8969 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association |
| record_format | Article |
| series | Makedonsko Farmacevtski Bilten |
| spelling | doaj-art-416df0c1275e43b19496ebcdec3894d92025-08-20T03:51:24ZengUniversity Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical AssociationMakedonsko Farmacevtski Bilten1409-86951857-89692025-12-01712435110.33320/maced.pharm.bull.2025.71.02.005Mycological profile of dermatomycoses in Macedonian patientsGordana Mirchevska0Emel Dauti Jahja1Sanja Kostova-Ilieva2Nadica Krsteva3Aleksandra Kacarska4Marija Kostovska-Micevska5Elena Trajkovska-Dokic6Zorica Zafirovik7Institute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute for the Public Health of the Republic of North Macedonia, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaInstitute of Microbiology and Parasitology, Faculty of Medicine, Ss. Cyril and Methodius University in, Skopje, “50 Divizija” 6, 1000 Skopje, Republic of North MacedoniaUniversity Clinic for Dermatology, Clinical Campus Mother Theresa, “Vodnjanska 17”, 1000 Skopje, Republic of North MacedoniaDermatomycoses are among the most common skin conditions that present a major public health problem. The aim of this study was to retrospectively analyse the mycological profile of dermatomycoses during a 6-year period (2017-2022). Specimens from 674 patients (384 nails 244 skin scrapings and 46 hair specimens) with dermatomycoses were examined. The specimens were evaluated with conventional mycological methods at the Institute of Microbiology and Parasitology, Skopje. Forty-seven percent of the samples were found to be culture positive. Samples from females were positive more frequently (192/317) than in males (125/317). The commonest age group was 11-20 years. The most prevalent etiological agents were non-dermatophyte molds56% (178/317), followed by yeasts in 30% (96/317), and dermatophytes in 13.6% (43/317). Almost 61% percent of the positive findings originated from nail specimens (192/317), 38% from skin scrapings (121/317), and 1.3% from hair specimens (4/317). Onychomycoses were caused by non-dermatophyte molds in 67% (128/192). Yeasts were identified in nail samples in 30% (57/192). Dermatophytes were agents of onychomycoses in 3.7% (7/192). Skin infections were caused by non-dermatophyte molds in 41.3% (50/121). Yeasts were identified in skin scrapings in 32% (39/121). Dermatophytes caused skin infections in 26.4% (32/121). Only 4 hair specimens were positive for dermatophytes. Our study reflects an increasing role of non-dermatophyte fungi as a causative agent of dermatomycoses, replacing dermatophytes. Clinicians’ awareness that molds can be contaminants of specimens, along with request for consecutive specimens can help in etiological diagnosis of dermatomycoses, leading to successful treatment and prevention of disease recurrence. http://bulletin.mfd.org.mk/volumes/Volume%2071_2/71_2_005.pdfdermatomycosesmoldsyeastsdermatophytes |
| spellingShingle | Gordana Mirchevska Emel Dauti Jahja Sanja Kostova-Ilieva Nadica Krsteva Aleksandra Kacarska Marija Kostovska-Micevska Elena Trajkovska-Dokic Zorica Zafirovik Mycological profile of dermatomycoses in Macedonian patients Makedonsko Farmacevtski Bilten dermatomycoses molds yeasts dermatophytes |
| title | Mycological profile of dermatomycoses in Macedonian patients |
| title_full | Mycological profile of dermatomycoses in Macedonian patients |
| title_fullStr | Mycological profile of dermatomycoses in Macedonian patients |
| title_full_unstemmed | Mycological profile of dermatomycoses in Macedonian patients |
| title_short | Mycological profile of dermatomycoses in Macedonian patients |
| title_sort | mycological profile of dermatomycoses in macedonian patients |
| topic | dermatomycoses molds yeasts dermatophytes |
| url | http://bulletin.mfd.org.mk/volumes/Volume%2071_2/71_2_005.pdf |
| work_keys_str_mv | AT gordanamirchevska mycologicalprofileofdermatomycosesinmacedonianpatients AT emeldautijahja mycologicalprofileofdermatomycosesinmacedonianpatients AT sanjakostovailieva mycologicalprofileofdermatomycosesinmacedonianpatients AT nadicakrsteva mycologicalprofileofdermatomycosesinmacedonianpatients AT aleksandrakacarska mycologicalprofileofdermatomycosesinmacedonianpatients AT marijakostovskamicevska mycologicalprofileofdermatomycosesinmacedonianpatients AT elenatrajkovskadokic mycologicalprofileofdermatomycosesinmacedonianpatients AT zoricazafirovik mycologicalprofileofdermatomycosesinmacedonianpatients |