Mechanism of astragaloside A against lung adenocarcinoma based on network pharmacology combined with molecular dynamics simulation technique

Mechanism of astragaloside A against lung adenocarcinoma based on network pharmacology combined with molecular dynamics simulation technique

Abstract This study explores the mechanisms of Astragaloside A (AS-A), a significant active ingredient in Astragalus, This traditional Chinese medicine is both a medication and a food, combating lung adenocarcinoma using network pharmacology, molecular docking, molecular dynamics, and experimental v...

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Bibliographic Details
Main Authors: Jian Ding, Qian Xue, Weizhen Guo, Gang Cheng, Lu Zhang, Tantan Huang, Di Wu, Jiabing Tong, Cheng Yang, Yating Gao, Zegeng Li
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Astragaloside A
Lung adenocarcinoma
Network pharmacology
Regulatory mechanism
Medicinal and edible plants
Online Access:https://doi.org/10.1038/s41598-025-94793-6
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