Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation
Currently， tumor and radiotherapy can result in physiological and functional damage to the salivary glands， significantly impacting the physiological and psychological well-being of patients. The repair of salivary gland injuries remains a challenging aspect of clinical treatment. Tissue regeneratio...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2025-01-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1740641062337-1135629558.pdf |
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| author | CHENG Taiqi, YAN Xing |
| author_facet | CHENG Taiqi, YAN Xing |
| author_sort | CHENG Taiqi, YAN Xing |
| collection | DOAJ |
| description | Currently， tumor and radiotherapy can result in physiological and functional damage to the salivary glands， significantly impacting the physiological and psychological well-being of patients. The repair of salivary gland injuries remains a challenging aspect of clinical treatment. Tissue regeneration engineering through cytokine-mediated stem cell directed differentiation offers a novel therapeutic approach for addressing salivary gland injuries. Embryonic stem cells （ESC） and induced pluripotent stem cells （iPSC）， with their potential for multidirectional differentiation and self-renewal， play a crucial role in regenerating and repairing salivary gland tissue. Building upon studies on classical tridermal differentiation of ESC/iPSC mediated by cytokines， this paper provides an extensive review on the research progress and future prospects of utilizing cytokine-mediated stem cell differentiation for salivary gland regeneration. |
| format | Article |
| id | doaj-art-416588c12d2e4fe2bc177fb9f023b321 |
| institution | OA Journals |
| issn | 0253-9802 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj-art-416588c12d2e4fe2bc177fb9f023b3212025-08-20T02:04:13ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022025-01-01561838710.12464/j.issn.0253-9802.2024-0241Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiationCHENG Taiqi, YAN Xing0Department of Stomatology， Beijing Friendship Hospital， Capital Medical University， Beijing 100050， ChinaCurrently， tumor and radiotherapy can result in physiological and functional damage to the salivary glands， significantly impacting the physiological and psychological well-being of patients. The repair of salivary gland injuries remains a challenging aspect of clinical treatment. Tissue regeneration engineering through cytokine-mediated stem cell directed differentiation offers a novel therapeutic approach for addressing salivary gland injuries. Embryonic stem cells （ESC） and induced pluripotent stem cells （iPSC）， with their potential for multidirectional differentiation and self-renewal， play a crucial role in regenerating and repairing salivary gland tissue. Building upon studies on classical tridermal differentiation of ESC/iPSC mediated by cytokines， this paper provides an extensive review on the research progress and future prospects of utilizing cytokine-mediated stem cell differentiation for salivary gland regeneration.https://www.xinyixue.cn/fileup/0253-9802/PDF/1740641062337-1135629558.pdfcytokine|pluripotent stem cell|directed differentiation|regeneration of salivary glands |
| spellingShingle | CHENG Taiqi, YAN Xing Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation Xin yixue cytokine|pluripotent stem cell|directed differentiation|regeneration of salivary glands |
| title | Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| title_full | Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| title_fullStr | Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| title_full_unstemmed | Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| title_short | Research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| title_sort | research progress of cytokine mediated pluripotent stem cells into salivary gland differentiation |
| topic | cytokine|pluripotent stem cell|directed differentiation|regeneration of salivary glands |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1740641062337-1135629558.pdf |
| work_keys_str_mv | AT chengtaiqiyanxing researchprogressofcytokinemediatedpluripotentstemcellsintosalivaryglanddifferentiation |