Poneratoxin as a key tool for investigating the relationship between sodium channel hypersensitivity and impaired nerve cell function

Poneratoxin as a key tool for investigating the relationship between sodium channel hypersensitivity and impaired nerve cell function

Abstract Poneratoxin (PoTX) is a 25-residue peptide derived from the venom of bullet ant, Paraponera clavata, recognized for its potent activation of NaV channel and pain-inducing effects in murine models. In this study, for the first time, we conducted the evaluation of the excitotoxicity of PoTX a...

Full description

Saved in:
Bibliographic Details
Main Authors: Zirui Lü, Xiandong Dai, Jianjie Xu, Mu Zhu, Bo Chen, Yongbiao Guo, Zhenhua Gao, Fanhua Meng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Poneratoxin
Transcriptomics
Proteomics
Neurological disorders
Online Access:https://doi.org/10.1038/s41598-025-11459-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items