Acute methemoglobinemia after a blast injury: a case report
Methemoglobin is a structurally modified form of hemoglobin incapable of binding oxygen, and elevated levels of methemoglobin cause tissue hypoxia. Occupational exposure to 2,4,6-trinitrotoluene, commonly called trinitrotoluene, causes methemoglobinemia. This case report describes a 27-year-old male...
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| Format: | Article |
| Language: | English |
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Korean Society of Traumatology
2022-08-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://jtraumainj.org/upload/pdf/jti-2021-0089.pdf |
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| author | Donghoon Kim Yoonhyun Lee Sung Yub Jeong Hojun Lee |
| author_facet | Donghoon Kim Yoonhyun Lee Sung Yub Jeong Hojun Lee |
| author_sort | Donghoon Kim |
| collection | DOAJ |
| description | Methemoglobin is a structurally modified form of hemoglobin incapable of binding oxygen, and elevated levels of methemoglobin cause tissue hypoxia. Occupational exposure to 2,4,6-trinitrotoluene, commonly called trinitrotoluene, causes methemoglobinemia. This case report describes a 27-year-old male sergeant who developed methemoglobinemia upon exposure to trinitrotoluene after a blast injury while welding the walls of tank shells. This is the first case of its kind in Korea. The patient had multiple burns in his abdomen and open fractures in his right leg. While his body temperature, heart rate, respiratory rate, arterial blood pressure, and chest X-ray were normal, arterial gas analysis revealed acute (methemoglobinemia concentration, 13.5%; oxygen saturation, 92.0%), probably caused by nitroglycerin exposure. Aspiration and adsorption through the skin and respiratory system were suspected to be the routes of entry. His methemoglobinemia normalized after 4 days after treating the wounds surgically, administering oxygen therapy, and performing blood transfusion. |
| format | Article |
| id | doaj-art-415f4c742b6040b486552c3181eb9cc0 |
| institution | Kabale University |
| issn | 2799-4317 2287-1683 |
| language | English |
| publishDate | 2022-08-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-415f4c742b6040b486552c3181eb9cc02025-01-16T04:51:18ZengKorean Society of TraumatologyJournal of Trauma and Injury2799-43172287-16832022-08-0135Suppl 1S15S1710.20408/jti.2021.00891102Acute methemoglobinemia after a blast injury: a case reportDonghoon Kim0Yoonhyun Lee1Sung Yub Jeong2Hojun Lee3 Department of Critical Care Medicine, Armed Forces Capital Hospital, Seongnam, Korea Armed Forces Trauma Center, Armed Forces Capital Hospital, Seongnam, Korea Armed Forces Trauma Center, Armed Forces Capital Hospital, Seongnam, Korea Armed Forces Trauma Center, Armed Forces Capital Hospital, Seongnam, KoreaMethemoglobin is a structurally modified form of hemoglobin incapable of binding oxygen, and elevated levels of methemoglobin cause tissue hypoxia. Occupational exposure to 2,4,6-trinitrotoluene, commonly called trinitrotoluene, causes methemoglobinemia. This case report describes a 27-year-old male sergeant who developed methemoglobinemia upon exposure to trinitrotoluene after a blast injury while welding the walls of tank shells. This is the first case of its kind in Korea. The patient had multiple burns in his abdomen and open fractures in his right leg. While his body temperature, heart rate, respiratory rate, arterial blood pressure, and chest X-ray were normal, arterial gas analysis revealed acute (methemoglobinemia concentration, 13.5%; oxygen saturation, 92.0%), probably caused by nitroglycerin exposure. Aspiration and adsorption through the skin and respiratory system were suspected to be the routes of entry. His methemoglobinemia normalized after 4 days after treating the wounds surgically, administering oxygen therapy, and performing blood transfusion.http://jtraumainj.org/upload/pdf/jti-2021-0089.pdfmethemoglobinemiatrinitrotolueneblast injuriescase reports |
| spellingShingle | Donghoon Kim Yoonhyun Lee Sung Yub Jeong Hojun Lee Acute methemoglobinemia after a blast injury: a case report Journal of Trauma and Injury methemoglobinemia trinitrotoluene blast injuries case reports |
| title | Acute methemoglobinemia after a blast injury: a case report |
| title_full | Acute methemoglobinemia after a blast injury: a case report |
| title_fullStr | Acute methemoglobinemia after a blast injury: a case report |
| title_full_unstemmed | Acute methemoglobinemia after a blast injury: a case report |
| title_short | Acute methemoglobinemia after a blast injury: a case report |
| title_sort | acute methemoglobinemia after a blast injury a case report |
| topic | methemoglobinemia trinitrotoluene blast injuries case reports |
| url | http://jtraumainj.org/upload/pdf/jti-2021-0089.pdf |
| work_keys_str_mv | AT donghoonkim acutemethemoglobinemiaafterablastinjuryacasereport AT yoonhyunlee acutemethemoglobinemiaafterablastinjuryacasereport AT sungyubjeong acutemethemoglobinemiaafterablastinjuryacasereport AT hojunlee acutemethemoglobinemiaafterablastinjuryacasereport |