Structural and functional roles of conserved residues of human papillomavirus (HPV) E2 protein and biological consequences

Abstract Background Human papillomavirus (HPV) is a prevalent viral pathogen that causes a variety of malignancies, including cervical cancer, one of the leading causes of cancer-related deaths among women worldwide. The HPV E2 protein is a central regulator of viral replication and oncogene express...

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Bibliographic Details
Main Authors: Sean Fletcher, Esther E. Biswas-Fiss, Subhasis B. Biswas
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-025-02903-7
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