Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_275_22 |
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| author | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick |
| author_facet | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick |
| author_sort | Prashant Mane |
| collection | DOAJ |
| description | Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made. |
| format | Article |
| id | doaj-art-414d0a7a70b045cbbe43124e8f96b917 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-414d0a7a70b045cbbe43124e8f96b9172025-01-22T15:29:53ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-07-0167246346510.4103/ijpm.ijpm_275_22Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literaturePrashant ManePrashant RamtekeAnand SinghAjay GogiaSaumyaranjan MallickExtranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.https://journals.lww.com/10.4103/ijpm.ijpm_275_22extransal nk/t cell lymphomagastric perforationnk/t cell lymphoma |
| spellingShingle | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature Indian Journal of Pathology and Microbiology extransal nk/t cell lymphoma gastric perforation nk/t cell lymphoma |
| title | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
| title_full | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
| title_fullStr | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
| title_full_unstemmed | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
| title_short | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
| title_sort | primary extranodal nk t cell lymphoma of stomach a case report and review of literature |
| topic | extransal nk/t cell lymphoma gastric perforation nk/t cell lymphoma |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_275_22 |
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