A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential

Toddalia asiatica (L.) Lam., belonging to Toddalia genus of Rutaceae family, is a folk medicine in China used for hundreds of years. The whole plant can be used as medicine, especially the root that used to be applied in the folk. In recent decades, with the in-depth research from domestic and forei...

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Main Authors: Zhi Zeng, Rui Tian, Jia Feng, Nian-an Yang, Lin Yuan
Format: Article
Language:English
Published: Springer 2021-08-01
Series:Saudi Pharmaceutical Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1319016421001006
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author Zhi Zeng
Rui Tian
Jia Feng
Nian-an Yang
Lin Yuan
author_facet Zhi Zeng
Rui Tian
Jia Feng
Nian-an Yang
Lin Yuan
author_sort Zhi Zeng
collection DOAJ
description Toddalia asiatica (L.) Lam., belonging to Toddalia genus of Rutaceae family, is a folk medicine in China used for hundreds of years. The whole plant can be used as medicine, especially the root that used to be applied in the folk. In recent decades, with the in-depth research from domestic and foreign researchers, it has gradually been discovered that the chemical components in T. asiatica are mainly coumarins and alkaloids. Its pharmacological effects are manifested in anti-inflammatory and analgesic, hemostatic coagulation, anti-tumor, treatment of cardiovascular diseases, etc. It has a wide range of clinical applications and significant effects on rheumatism, pain, wound bleeding, and bruises. Due to its important research value, in this article, the chemical compositions and pharmacological effects of T. asiatica are comprehensively expounded in recent years in order to provide a reference for the related research and application of this medicinal material, which were carried out through a bibliometric search using the Science Citation Index- Expanded (SCIE) database, web of science, Google scholar and Chinese National Knowledge Infrastructure (CNKI) and all that.
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spelling doaj-art-414b3ceb51214b578bcc097335faef202025-08-20T03:55:35ZengSpringerSaudi Pharmaceutical Journal1319-01642021-08-0129878179810.1016/j.jsps.2021.05.003A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potentialZhi Zeng0Rui Tian1Jia Feng2Nian-an Yang3Lin Yuan4Hubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, ChinaHubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, ChinaHubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, ChinaHubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, ChinaCorresponding author.; Hubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, ChinaToddalia asiatica (L.) Lam., belonging to Toddalia genus of Rutaceae family, is a folk medicine in China used for hundreds of years. The whole plant can be used as medicine, especially the root that used to be applied in the folk. In recent decades, with the in-depth research from domestic and foreign researchers, it has gradually been discovered that the chemical components in T. asiatica are mainly coumarins and alkaloids. Its pharmacological effects are manifested in anti-inflammatory and analgesic, hemostatic coagulation, anti-tumor, treatment of cardiovascular diseases, etc. It has a wide range of clinical applications and significant effects on rheumatism, pain, wound bleeding, and bruises. Due to its important research value, in this article, the chemical compositions and pharmacological effects of T. asiatica are comprehensively expounded in recent years in order to provide a reference for the related research and application of this medicinal material, which were carried out through a bibliometric search using the Science Citation Index- Expanded (SCIE) database, web of science, Google scholar and Chinese National Knowledge Infrastructure (CNKI) and all that.http://www.sciencedirect.com/science/article/pii/S1319016421001006Toddalia asiaticaFolk medicineChemical compositionPharmacological effect
spellingShingle Zhi Zeng
Rui Tian
Jia Feng
Nian-an Yang
Lin Yuan
A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
Saudi Pharmaceutical Journal
Toddalia asiatica
Folk medicine
Chemical composition
Pharmacological effect
title A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
title_full A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
title_fullStr A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
title_full_unstemmed A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
title_short A systematic review on traditional medicine Toddalia asiatica (L.) Lam.: Chemistry and medicinal potential
title_sort systematic review on traditional medicine toddalia asiatica l lam chemistry and medicinal potential
topic Toddalia asiatica
Folk medicine
Chemical composition
Pharmacological effect
url http://www.sciencedirect.com/science/article/pii/S1319016421001006
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