Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI

Abstract Monoclonal antibodies (mAb) are key therapeutic agents in cancer immunotherapy and exert their effects through Fc receptor-dependent and -independent mechanisms. However, the nanoscale receptor reorganization resulting from mAb binding and its implications for the therapeutic mode of action...

Full description

Saved in:
Bibliographic Details
Main Authors: Isabelle Pachmayr, Luciano A. Masullo, Susanne C. M. Reinhardt, Jisoo Kwon, Maite Llop, Ondřej Skořepa, Sylvia Herter, Marina Bacac, Christian Klein, Ralf Jungmann
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61893-w
Tags: Add Tag
No Tags, Be the first to tag this record!