Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities
Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactiva...
Saved in:
Main Authors: | Ignacio M. Seropian, Germán E. González, Sebastián M. Maller, Daniel H. Berrocal, Antonio Abbate, Gabriel A. Rabinovich |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2018/8696543 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Role of Galectins as Modulators of Metabolism and Inflammation
by: Monica Fengsrud Brinchmann, et al.
Published: (2018-01-01) -
Galectin-3 Is a Potential Mediator for Atherosclerosis
by: Ziyu Gao, et al.
Published: (2020-01-01) -
Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers
by: Diego J. Laderach, et al.
Published: (2013-01-01) -
Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities
by: Liu C, et al.
Published: (2025-01-01) -
Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines
by: Jovanović Krivokuća Milica, et al.
Published: (2024-01-01)