Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury

Objective(s): In this study, we aimed to investigate the protective effect of Thymoquinone (THQ) against testicular damage caused by Methotrexate (MTX).Materials and Methods: This study consists of 5 groups: Control, Olive oil, THQ, MTX, and MTX+THQ. At the end of the experiment, spermiogram analysi...

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Bibliographic Details
Main Authors: Emin Kaymak, Tayfun Ceylan, Ali Akin, Nurhan Kuloğlu, Meryem Sayan, Necla Değer, Esra Önal, Aysegul Yildirim, Derya Karabulut
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2024-11-01
Series:Iranian Journal of Basic Medical Sciences
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Online Access:https://ijbms.mums.ac.ir/article_24663_87432a59cf91342ee23ccddd5b0d1bad.pdf
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