A N7-methylguanosine modified circular RNA, circIPP2A2, promotes malignant behaviors in hepatocellular carcinoma by serving as a scaffold in modulating the Hornerin/PI3K/AKT/GSK3β axis

A N7-methylguanosine modified circular RNA, circIPP2A2, promotes malignant behaviors in hepatocellular carcinoma by serving as a scaffold in modulating the Hornerin/PI3K/AKT/GSK3β axis

Abstract Despite the advancements in treatment strategies, the long-term survival of hepatocellular carcinoma (HCC) is still pessimistic. Therefore, understanding the mechanisms of hepatocellular carcinoma may offer substantial benefits for patients. Our previous research has revealed that Hornerin...

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Main Authors: Zeyi Guo, Zhongzhe Li, Jinhao Guo, Luxiang Gan, Haiyu Mo, Jiajun Zhang, Yu Fu, Yi Wang, Meixian Jin, Yanping Wu, Qingyu Xie, Kunjiang Tan, Chunming Wang, Yuyan Xu, Guolin He, Lei Cai, Yi Gao, Mingxin Pan, Shunjun Fu
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07248-7
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