Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults

Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults

Abstract Background Blood-based biomarkers hold significant promise for the early detection and diagnosis of Alzheimer’s disease (AD) and other dementias. Age-related changes in blood levels of AD biomarkers are well-documented but poorly understood. Epigenetic clocks are mathematical models based o...

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Bibliographic Details
Main Authors: Myriam Fornage, Wassim Tarraf, Martha L. Daviglus, Charles DeCarli, Kevin A. Gonzalez, Carmen R. Isasi, Sayaka Kuwayama, Melissa Lamar, Bonnie E. Levin, Humberto Parada, Alberto R. Ramos, Tatjana Rundek, Bharat Thyagarajan, Hector M. González
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Clinical Epigenetics
Subjects:
Hispanic/Latino
Epigenetic aging, blood-based biomarkers
Alzheimer’s disease
Epigenetic clocks
Online Access:https://doi.org/10.1186/s13148-025-01941-w
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