Case report: special imaging features in a uremic patient with intracranial infection caused by Ralstonia mannitolilytica, almost misdiagnosed as demyelinating disease
Ralstonia mannitolilytica is a very rare pathogen that causes intracranial infection. It is commonly found in immunocompromised patients and is resistant to multiple antibiotics. In this case report, we present a case of human central nervous system infection caused by Ralstonia mannitolilytica, whi...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1513771/full |
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| Summary: | Ralstonia mannitolilytica is a very rare pathogen that causes intracranial infection. It is commonly found in immunocompromised patients and is resistant to multiple antibiotics. In this case report, we present a case of human central nervous system infection caused by Ralstonia mannitolilytica, which was initially misdiagnosed as demyelinating disease due to the specific imaging findings. This case had concurrent uremia and a good response to meropenem under continuous peritoneal dialysis. The diagnosis is mainly based on cerebrospinal fluid analysis and targeted genetic testing by next generation sequencing (NGS). However, the patient had a poor prognosis due to uncontrollable gastrointestinal bleeding and related complications during long-term bed rest. We hope that this case will attract more attention and provide relevant reference for the diagnosis and treatment of other similar patients. |
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| ISSN: | 2296-858X |