Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study

Background. The morning home blood pressure (BP) rise is a significant asymptomatic target organ damage predictor in hypertensives. Our aim was to evaluate determinants of home-based morning-evening difference (MEdiff) in Argentine patients. Methods. Treated hypertensive patients aged ≥18 years part...

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Main Authors: Lucas S. Aparicio, Jessica Barochiner, Paula E. Cuffaro, José Alfie, Marcelo A. Rada, Margarita S. Morales, Carlos R. Galarza, Marcos J. Marín, Gabriel D. Waisman
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2014/569259
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author Lucas S. Aparicio
Jessica Barochiner
Paula E. Cuffaro
José Alfie
Marcelo A. Rada
Margarita S. Morales
Carlos R. Galarza
Marcos J. Marín
Gabriel D. Waisman
author_facet Lucas S. Aparicio
Jessica Barochiner
Paula E. Cuffaro
José Alfie
Marcelo A. Rada
Margarita S. Morales
Carlos R. Galarza
Marcos J. Marín
Gabriel D. Waisman
author_sort Lucas S. Aparicio
collection DOAJ
description Background. The morning home blood pressure (BP) rise is a significant asymptomatic target organ damage predictor in hypertensives. Our aim was to evaluate determinants of home-based morning-evening difference (MEdiff) in Argentine patients. Methods. Treated hypertensive patients aged ≥18 years participated in a cross-sectional study, after performing home morning and evening BP measurement. MEdiff was morning minus evening home average results. Variables identified as relevant predictors were entered into a multivariable linear regression analysis model. Results. Three hundred sixty-seven medicated hypertensives were included. Mean age was 66.2 (14.5), BMI 28.1 (4.5), total cholesterol 4.89 (1.0) mmol/L, 65.9% women, 11.7% smokers, and 10.6% diabetics. Mean MEdiff was 1.1 (12.5) mmHg systolic and 2.3 (6.1) mmHg diastolic, respectively. Mean self-recorded BP was 131.5 (14.1) mmHg systolic and 73.8 (7.6) mmHg diastolic, respectively. Mean morning and evening home BPs were 133.1 (16.5) versus 132 (15.7) systolic and 75.8 (8.4) versus 73.5 (8.2) diastolic, respectively. Significant beta-coefficient values were found in systolic MEdiff for age and smoking and in diastolic MEdiff for age, smoking, total cholesterol, and calcium-channel blockers. Conclusions. In a cohort of Argentine medicated patients, older age, smoking, total cholesterol, and use of calcium channel blockers were independent determinants of home-based MEdiff.
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institution Kabale University
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spelling doaj-art-4105eb01a9e743e19aadc0e8d88b58832025-02-03T05:53:55ZengWileyInternational Journal of Hypertension2090-03842090-03922014-01-01201410.1155/2014/569259569259Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home StudyLucas S. Aparicio0Jessica Barochiner1Paula E. Cuffaro2José Alfie3Marcelo A. Rada4Margarita S. Morales5Carlos R. Galarza6Marcos J. Marín7Gabriel D. Waisman8Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaHypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, ArgentinaBackground. The morning home blood pressure (BP) rise is a significant asymptomatic target organ damage predictor in hypertensives. Our aim was to evaluate determinants of home-based morning-evening difference (MEdiff) in Argentine patients. Methods. Treated hypertensive patients aged ≥18 years participated in a cross-sectional study, after performing home morning and evening BP measurement. MEdiff was morning minus evening home average results. Variables identified as relevant predictors were entered into a multivariable linear regression analysis model. Results. Three hundred sixty-seven medicated hypertensives were included. Mean age was 66.2 (14.5), BMI 28.1 (4.5), total cholesterol 4.89 (1.0) mmol/L, 65.9% women, 11.7% smokers, and 10.6% diabetics. Mean MEdiff was 1.1 (12.5) mmHg systolic and 2.3 (6.1) mmHg diastolic, respectively. Mean self-recorded BP was 131.5 (14.1) mmHg systolic and 73.8 (7.6) mmHg diastolic, respectively. Mean morning and evening home BPs were 133.1 (16.5) versus 132 (15.7) systolic and 75.8 (8.4) versus 73.5 (8.2) diastolic, respectively. Significant beta-coefficient values were found in systolic MEdiff for age and smoking and in diastolic MEdiff for age, smoking, total cholesterol, and calcium-channel blockers. Conclusions. In a cohort of Argentine medicated patients, older age, smoking, total cholesterol, and use of calcium channel blockers were independent determinants of home-based MEdiff.http://dx.doi.org/10.1155/2014/569259
spellingShingle Lucas S. Aparicio
Jessica Barochiner
Paula E. Cuffaro
José Alfie
Marcelo A. Rada
Margarita S. Morales
Carlos R. Galarza
Marcos J. Marín
Gabriel D. Waisman
Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
International Journal of Hypertension
title Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
title_full Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
title_fullStr Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
title_full_unstemmed Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
title_short Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study
title_sort determinants of the morning evening home blood pressure difference in treated hypertensives the hiba home study
url http://dx.doi.org/10.1155/2014/569259
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