Concurrent Presentation of Posterior Reversible Encephalopathy Syndrome and Spontaneous Coronary Artery Dissection in a Postpartum Patient Without Traditional Risk Factors: A Case Report
Posterior reversible encephalopathy syndrome (PRES) and spontaneous coronary artery dissection (SCAD) are rare, life-threatening postpartum conditions, often linked to hypertensive disorders or hormonal changes. Their co-occurrence without traditional risk factors is exceptionally rare. We report a...
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2025-07-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.1049 |
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| Summary: | Posterior reversible encephalopathy syndrome (PRES) and spontaneous coronary artery dissection (SCAD) are rare, life-threatening postpartum conditions, often linked to hypertensive disorders or hormonal changes. Their co-occurrence without traditional risk factors is exceptionally rare. We report a 29-year-old woman without hypertension who developed PRES and SCAD on postoperative day 1 after an uncomplicated cesarean delivery. She presented with altered mental status, seizure-like activity, and chest pain. Magnetic resonance imaging confirmed PRES, whereas coronary angiography identified SCAD. Management included the administration of levetiracetam for PRES and aspirin, beta-blockers, and an angiotensin-converting enzyme inhibitor for SCAD. This case highlights diagnostic challenges and the need for further research into shared mechanisms like endothelial dysfunction. |
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| ISSN: | 2767-7664 |